The Morphology of Functional Activity in the Ganglion 
Gells of the Crayfish, Cambarus virilis. 
The Niimerical Statement of the Nucleus-plasma Norm and of its 
Upset in Prolonged Activity. 
By 
David H. Dolley. 
(Froiii the Pathological Laboratoiy of the University of Missouri.) 
Witli 5 figures and 8 tables in the text and plates XXIV — XXVI. 
Synopsis. 
Page 
Introduction 486 
Source of material 487 
Experimental methods 488 
Technic of fixation and staining 490 
Technic of size computation and comparison 491 
The technic of cell measurements 491 
The calculations of volume and of nucleus-plasma coefficients .... 494 
The technic of curve construction 495 
Introductory Statement regarding the significance of the size changes and the argu- 
ment for their correlation with functional activity 496 
The anaiysis of ceU tj'pes and the presumptive Separation into motor and sensory 
groups 499 
The changes produced by activity exclusive of those of absolute and relative size 503 
The variations in the absolute and relative sizes of the cell and its nucleus and in 
the nucleus-plasma relation therefrom resulting 507 
The source and extent of the data 507 
Comparison of the stimulated with the normal animals 511 
The Statement of the normal nucleus-plasma relation 518 
The upset of the nucleus-plasma relation in prolonged activity . . . 524 
The nucleus-plasma relation in foetal and infantile animals 528 
The seasonal variations of cell States and the indications of recovery 531 
Deductions regarding the mechanics of nerve cell activity — the relation of the 
size changes to the formation of chromatin 532 
General considerations regarding the significance of the celliüar hypertrophy . . 544 
Summary 545 
Conclusions 547 
Archiv f. Zellforschung. IX. 
33 
