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IOWA ACADEMY OF SCIENCES 
which the branches ramify.” Sihler thinks that what has been seen 
in this regard by Kuhne and others is derived from Henle’s sheath. To 
quote: “I find that the so-called ‘Sohlenstanz’ of Kuhne is derived from 
Henle’s sheath.” 
Huber-Dewitt conclude that the end branches of the axis-cylinder 
are entirely under the sarcolemma. To use their own language: ‘‘Two 
cross sections are shown in Figs. 13 and 14. It may here be seen that 
the ramifications of the axis-cylinder are under the sarcolemma termin- 
ating in a relatively thin layer of sarcoplasma.” Kuhne is mentioned by 
them as holaing a similar view. According to Sihler, Engelmann, Klein, 
Gerlach, Frey, and Waldeyer are also of this same opinion. Sihler him- 
self, however, concludes that with perhaps some qualifications these end- 
branches are epilemmal. The following statements from him will serve 
to show his position: “The endings of motor nerves in striped muscle 
remain on the outside of the sarcolemma. What may be the exact con- 
dition of things at the points where muscle and nerve fibre are in actual 
contact — whether the sarcolemma and neurilemma are wanting there or 
perforations exist — I cannot say. The precise relation of muscle to nerve 
here is an unsolved and difficult problem.” Dogiel in the following 
language states that they are hypolemmal “die Marksubstanz aber sammt 
dem Achsencylinder tritt unter das Sarcolemma”.. Huber-Dewitt quote 
Rhetzius as being in doubt whether the end branches are epi- or hypo- 
lemmal. Wilson takes the view that the larger branches of the endings 
lie over the sarcolemma and at some distance from it, while small fibril- 
lae possessing a terminal knob come off lying either within or under the 
sarcolemma. 
Sihler states that Henle’s sheath ends before the muscle fibre is 
reached and is open so that the axis-cylinder with its neurilemma appears 
like an arm emerging from a sleeve, while the sheath of Schwan covers 
the end fibres down to their tips and is provided with nuclei. Huber- 
Dewitt thinks that the sarcolemma and neurilemma become continuous 
with each other at the point where the nerve fibre, as they claim, pierces 
the sarcolemma. This small area made up of both sheaths they call 
telolemma and its nuclei if any are found at this point, telolemma 
nuclei. The following statement from Dogiel will show his attitude: 
“In ersten Falle tritt die markhaltige Nervenfaser an irgend eine Stelle 
der Muskelfaser heran, verliert in dem Sarkolemma ihre Schwan, ’sche 
und Henlische Scheide” which practically agrees with the last preceding 
writer. 
As to the appearance and disposition of these ultimate branches, 
Dogiel thinks they are devoid of any sheath, are thickened, toothed and 
run along the muscle fibre frequently ending in a knob. He thinks they 
neither go to any neighboring muscle fibres nor form any plexuses. 
Wilson thinks on the other hand that they are covered by a sort of a 
sheath formed from the ordinary nerve coverings and the sarcolemma, but 
are non-medullated. He also thinks that some of them end in the inter- 
muscular connective tissue, and that others go to neighboring fibres. 
Plexuses are found at times also, he thinks. Sihler remarks that the 
