
          Williamsbourgh. [Williamsburg] 1. Febr. [February] 1853.


 My high revered dear Sir!


 It is our fate, to must combatt [combat] with all
 possible hardship. 


 Not sooner than this day it was possible to
 my wife to leave the house; she has suffered till 
 now very much and at last even the vesicatory I
 had applicated on her arm has effectuated a vehement 
 erysipelous [erysipelatous] inflammation, singular, and
 being not yet wholly vanished.


 Who should not be despondent to see paralyzed
 himself in every direction? Might the heaven
 at least preserve us a good health, for to view less
 sorrowful to the future.


 Perhaps we may hope, that You, dear Sir, will
 think us neither negligent, nor unworthy to Your
 kind benevolence, when on account of such deplorable
        