IOWA ACADEMY OF SCIENCE 
193 
THE RELATIVE FREQUENCY OF ARTERIO SCLEROSIS OF THE VARIOUS 
ARTERIES. 
BY W. E. SANDEES. 
The present paper is a preliminary report of one phase of a series of arterio 
sclerotic cases which the author studied during the summer of 1908 while 
engaged in pathological studies in Berlin and Munich. 
A brief autopsy report was taken of each case, especial attention being given 
to the condition of the heart and kidneys. 
The macroscopic appearance of the vessels were noted at the autopsy and 
specimens taken for further microscopic study. The vessels selected were the 
arch of the Aorta, the Pulmonary, the Coronaries, the Splenic, the Renals, the 
Internal Carotid, just below the circle of Willis, or pre fossi sylvii, and occasion- 
ally various other arteries. 
The material included only selected cases from some 300 post-mortems with a 
view of elimina.ting syphilitic endo and mesarteritis and including only early 
cases of the so-called senile artero sclerosis, the primary object being to determ- 
ine the nature and location of the initial process and if the same be of a circum- 
scribed or diffuse character. The critical phases of the subject I shall not dis- 
cuss in this paper but shall reserve it for a later contribution. 
The specimens v/ere fixed in 2 per cent Formol cut with the freezing micro- 
tome and stained with Hsematoxoylin and Sudan iii, for degenerative changes, 
and Carmine and Weigert’s elastic stain for the changes in the elastic elements. 
The following is an epitome of twenty cases. In describing the extent of the 
process I have used the terms minimal, moderate and pronounced. It must be 
understood, however, that these terms are used only in a relative sense as the 
cases Trere most all as I have, previously stated in the initial or early stage of 
the disease. 
Case I. Male, 51. Died from carcinoma of the cesophigus. 
The thoracic aorta was free, the abdominal aorta minimal sclerosis. The 
left coronary and splenic minimal, the right renal moderate and the left renal 
and the right femoral pronounced changes. 
Case II. Male, 56. Died from Addison’s disease. 
Thoracic and abdominal pronounced, both carotids and both coronaries 
moderate, splenic, both renals and the coeliac axis minimal and the basalar 
and cerebrals free. 
Case III. Male, 46. Died from purulent meningitis. 
The thoracic and abdominal aorta, the subclavian, both carotids, the splenic 
and both renals minimal, the left coronary pronounced, the right coronary 
and cerebrals free. 
Case IV. Male, 47. Died from a myxo' sarcomatous tumor of the medias- 
tinum. 
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