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changes. This man also had a gastric ulcer which very possibly was induced 
by sclerosis of the gastric vessels. 
Case XIV. Male, 40. Died from tubercular meningitis and pulmonary tuber- 
culosis. 
The aorta from the arch to the iliacs showed moderate sclerotic patches. 
The pulmonary minimal, also the coronaries, the inferior thyroid, the pre fossi 
sylvii and the right common iliac moderately affected. 
Case XV. Male, 31. Diagnosis cardiac insufficiency. Right side pleurisy. 
Aortic arch pronounced plate like sclerotic elevations. Thoracic aorta mini- 
mal pessary like elevations around the orifices of some of the intercostals. 
The coronaries, the renals were very slightly affected, while the splenic and 
pre fossi sylvii were negative. 
Case XVI. Male, 54. Died from heart disease, odcema of the extremities 
marked. 
Aorta and both renals moderate, coronaries minimally affected. This may 
have been syphilitic. 
Case XVII. Male, 62. Died of sepsis from a carbuncle. Had also chronic 
interstitial nephritis. 
Aorta pronouncedly sclerotic with atheromatous degeneration in the abdo- 
minal portion. Coronaries, splenic and renals moderately affected, arteria pre 
fossi sylvii very slightly. 
Case XVIII. Female, 48. Died from heart disease, old mitral stenosis and 
acute endocarditis. 
Aorta minimally, stem of pulmonary moderately, while the medial and the 
smaller sized pulmonary vessels are pronouncedly sclerotic. The splenic, re- 
nals and vertebral show only minimal sclerosis. 
Case XIX. Female, 60. Died from some acute infection. 
Pronounced sclerosis with some atheroma of the aorta, both coronaries and 
both renals moderately and the splenic and pre fossi sylvii only slightly af- 
fected. ' 
Case XX. Male, 40. Died from carcinoma of the pancreas. 
The aortis arch, moderate circumscript patches near the origin of the caro- 
tids and coronaries. Abdominal portion atheromatous changes some in the 
ulcerative stage, the coronaries themselves only minimal sclerosis. Renals 
coeliac and pulmonalis free. 
These twenty cases showed four between 30 and 40, seven between 40 and 
50, four between 50 and 60, three between 60 and 70, and two between 70 and 
80. The youngest was 31 and the oldest 76. 
Chart I. * = not studied; o = negative; i, ii, iii = minimal, moderate and 
pronounced sclerosis. 
Of the twenty cases studied, nineteen or 95 per cent revealed sclerosis of the 
aortio arch; fourteen or 70 per cent of the thoracic; fifteen or 75 per cent of the 
abdominal; fifteen or 75 per cent of the left coronary; twelve of the eighteen 
right coronaries, or 60 per cent; thirteen of the left renals, or 65 per cent; fif- 
teen or 75 per cent of the right renals; twelve out of nineteen, or 57 per cent, 
of the splenics; five of the thirteen, or 37 per cent, of the pre fossi sylvii. In 
general the degree of the process is in accord with its frequency. 
Without entering into detail I may state that the result of my study has 
demonstrated conclusively that so far as histological evidence is concerned the 
process is essentially limited to the intima being of the hyperplastic connec- 
