26 
DR. C. H. JONES ON THE STRUCTURE, DEVELOPMENT 
(7.) A piece of Human liver of healthy appearance, but the cells around the intra- 
lobular veins contain a great deal of deep reddish yellow matter. Four extracts were 
made. 1st. Chloroform gave a beautiful crystalline residue of solid fat, partly 
coloured with yellow spots. Pettenkofer’s test gave no trace of cholic acid ; nitric 
acid gave a very slight purple tinge, which changed into green. 2nd. Ether gave an 
abundant deposit of oils and fats which produced a slight reaction with nitric acid, 
but no trace of cholic acid with sugar and sulphuric acid. 3rd. Alcohol gave a 
coloured extract containing fatty matters, more solid than those from ether, but 
showing on being tested no trace of cholic acid. 4th. Water ; the extract gave no 
trace of cholic acid, but on the addition of liquor potassse and sulphate of copper, a 
portion of the copper was reduced by boiling to the red oxide, and the supernatant 
liquor remained of a beautiful azure tint, in which no change was effected by heat 
on long standing. This azure colour, as in (4), probably indicates the presence of 
glycocol, which is united with cholic to form the glycocholic acid of the bile. The 
fatty matter saponified by potash and extracted with alcohol gave no trace of cholic 
acid. 
(8.) A cat’s liver ; the animal had been treated with calomel, and had taken twelve 
grains in twenty hours. The aqueous extract gave some trace of sugar and of fat, 
but none of cholic acid. 
(9.) Liver of a man who died with suppuration in all the divisions of the portal 
vein, the smaller branches being blocked up. The interior cells of the lobules were 
filled with yellow matter. The aqueous solution of the parenchyma gave no indica- 
tion of cholic acid or sugar, but with Trommer’s test a solution of fine blue colour 
was obtained, from which nothing fell down on boiling or after long standing. This 
seems to indicate the presence of glycocol. The gall-bladder was inflamed ; its con- 
tents gave no reaction of cholic acid or sugar. 
(10.) Liver of a female extremely fat ; died with tubercular cavities in lungs. The 
presence of sugar and probably of glycocol was ascertained by Trommer’s test. 
The contents of the gall-bladder were thick and of a dark saffron colour ; contained 
very little cholic acid, no sugar, a great deal of colouring matter. 
(11.) Liver of a patient who died from inanition ten days after having cut his 
throat ; it gave no trace of sugar nor of glycocol. 
(12.) Liver of a distinct yellow colour, extremely fatty, the cells gorged with oil, 
and containing much yellow matter also. The aqueous solution gave a deposit of 
suboxide of copper with Trommer’s test, and the supernatant liquor remained of a 
purple colour, thus indicating the presence of sugar and glycine. The alcoholic 
solution gave a beautiful reaction with nitric acid (first green and then purple), cha- 
racteristic of the colouring matter of the bile, but no trace of cholic acid; it con- 
tained also a small quantity of fatty matter. The female from whom this liver was 
taken, was jaundiced at the time of her death. 
The conclusions which may be drawn from the foregoing observations are — 
