or UBEA AOT) UEINAEY WATEE. 
793 
of urea was not so high as it had been on the previous day, but the excretion was very 
large relatively at midnight on both days. On the fourth day, before additional food 
was given, the maximum was equal to that on the preceding day, and occurred so early 
as 11 A.M. ; but after the additional food the elimination of urea again increased, and the 
maximum of the whole day occurred between 7 and 12 P.M. On this day the maximum 
increase with the bread and water was lO'l grs. per hour, or 75 per cent, of the basis 
quantity ; but after the additional food and late in the evening it rose to 16 grs. per hour 
and 117 per cent, of the basis quantity. 
It is to be remarked that, after three days insutficient dietary and the addition of 
abundant food in the afternoon of the foui’th day, the rate of elimination on the follow- 
ing night was scarcely, if at all, mcreased — a circumstance due doubtless to the fixation 
of the nitrogen. 
The rate of the elimination of mine on the first day followed the usual course in 
health, and attained a maximum of 6 '82 oz. per hoiu’. On the second and third day the 
rate sensibly declined, and on the day "with cofiee it was relatively high in the evening. 
On the fourth day, before additional food had been taken, the rate was the least which 
had occurred, and was so low at midday as 1‘8 oz. per hour. 
Hence this series of experiments showed that a full dietary of bread and water, or tea 
or cofiee, does not vary the hourly progression of the urinary secretion from that which 
is found with mixed food, but it fails to yield comfort to the system, and also that with 
48 oz. of fluid per day the rate of urinary secretion fell considerably below that which 
ordinarily occurs. AYhen water is given with bread alone it should be of the temperature 
of the body. 
5. Cycle of the Week. 
There are no experiments on record in reference to this subject. Sunday was a day 
of strong contrast vrith other days of the week ; for I took almost perfect rest on that 
day, and also ate a little additional solid food, as follows: — 
18G0. 1861. 
March. 
April. 
May. 
June. 
July. 
February. 
March. 
oz. 
oz. 
oz. 
oz. 
oz. 
oz. 
oz. 
20 
6-3 
•3 
•1 
2-7 
2-6 
1-5 
The comparison of the urinary excretion on Sunday and on week days may be made 
in two ways. As compared with the average returns of all the days of the year, the 
excretion of urea was on Sundays 533-4 grs. against 519 grs. on all days combined; but 
as many influential causes of variation occuiTed during each week which did not occur 
on Sundays, a more just comparison may be made with the average of those days on 
which no known cause of variation occurred. I have collected all the unexceptional 
days, and have taken the average of them in each month, as is shown in the following 
Table : — 
