728 
DE. E. SmTH OX THE ACTIOX 
December 27 (5 exps.), Plate XXXVI. fig. 50.— i an oz. of only moderately good mm, 
which had been used in the experiments on inhalation, and so weak as -944 spec. grav. 
( 37-5 per cent.), with 2 oz. of cold water, taken eveiy'- quarter of an hour, gave the fohow- 
ing increase in the quantity of carbonic acid evolyed after each dose -14 gr., -43 gr., 
*2 gr., and -66 gr., showing a continuous increase. The maximum increase in the quan- 
tity of air inspired was 49 cubic inches after the last dose, and the propoidion of the 
carbonic acid to the inspired air was somewhat reduced in consequence of the dispro- 
portionate increase of the latter. The rate of respiration was slightly increased with Ae 
first dose, and as slightly decreased with the subsequent ones, whilst the rate of pulsation 
was also slightly increased. The amount of vapour exhaled per minute in the exphed 
air varied from a decrease of -3 gr. and -2 gr. after the second and third doses, when the 
respiration felt feeble and there was sighmg, to an increase of -04 gr. and -06 gr. after 
the first and fourth doses. There was, however, a progressive decrease to each 100 cubic 
inches of inspired air, as follows;— '742 gr. (basis), '7 gr., ‘67 gr., 65 gi., and 67 gr., 
after succeeding doses. 
Bum and Milk .— 12 (8 exps.), Plate XXXVI. fig. 51. 1^- oz. of Xay rum, 
with 1 pint of good new milk, produced in myself and Mr. Moul an average mcrease 
in the carbonic acid of -73 gr. and -66 gr. per minute, whilst the maxima^ of increase 
were -9 gr. and 1-38 gr. per minute respectively. The quantity of air was increased 25 
cubic inches and 18 cubic inches per minute, with a diminution also of 42 cubic inches in 
the latter (Mr. Moul). The rate of respiration declined, and very much so in Mr. Moi l, 
whilst that of pulsation wns increased. The depth of respiration was increased in both. 
Sherry IFme.— April 2 (5 exps.). May 5 (5 exps.). May 6 (7 exps.), Plate XXX^ I. 
fig. 53 . 3 oz. of tolerably good sherry wine, alone, produced in myself, on two occa- 
sions, an average increase of -19 gr. and *3 gr., and on another occasion an average 
decrease of -32 gr. of carbonic acid per minute. The maxima of mcrease were -06 gr. 
and -44 gr., and of decrease -52 gr. per minute on the several occasions. In iSD. Moul 
the average decrease was *32 gr., and increase -926 gr. and -21 gr. per minute; with 
maxima of decrease -9 gr., and of increase 1-44 gr. and -82 gr. per minute. The quantity 
of air was lessened in myself in all the inquiries, but chiefly in the fii'st one, and least m 
the last ; whilst in Mr. Moul it varied in the two former and was reduced in the last. 
The rate of respiration in both fell, and chiefly so in the fii’st experiment, uhilst thut 
of pulsation rose in myself, and was unchanged in Mr. Moul. 
Inhalation of Alcohols. 
I have made several experiments with a view to determine the influence ot the lola- 
tile matters of wines and spirits when inhaled, but the uneasy feeling in the lungs u hich 
followed each experiment made me fear the effect of a too prolonged series. I placed 
3 or 4 oz. of the fluid for examination in a Woulfe’s bottle, and inspired ah at the ordi- 
nary temperature which had passed dhectly over it, taking care to shake the fluid fre- 
quently. 
