244 
DR. BENCE JONES ON THE VARIATIONS 
A.M. A.M. 
h m h m oz. Spec. gr. Total carb. of soda required. 
(14.) Total quantity from 7 30 to 7 30=46^ 1 022*4= 14'99 grains 
_ [about 8*80 measures of acid, 
1 per 1000 grs. of urine. 
(15.) Total quantity from 7 30 to 7 30= 35f 1027*1 = 16*87 grains 
=aboutl2*65 acid.perlOOOurine. 
( 1 6.) Total quantity from 7 30 to 7 30 = 44 1 023*8 = 14*31 grains 
=about 8*78acid.perl000urine. 
During each of the three following days, three drachms of dilute sulphuric acid, 
specific gravity 1*10775 were taken, in three and a half ounces of distilled water; the 
greater part from 9 to 12 a.m. 
A.M. A.M. 
h m h m oz. Spec, gr. Total carb. of soda required. 
(17.) Total quantity from 7 30 to 7 30 = 40 1026*2= 17‘59 grains 
_ J ^bout 1 1*88 measures of acid. 
1 per 1000 grs. of urine. 
(18.) Total quantity from 7 30 to 7 30=54 1020*3= 17*64 grains 
=about 8*82acid.perl000urine. 
(19.) Thick from urates . . . =40 1028*6 = 25*92 grains 
=aboutl 7*30acid.perl000urine. 
From the comparison of the total amount of carbonate of soda required to neu- 
tralize the acidity of the urine, there is no doubt that sulphuric acid does slightly 
increase the acidity of the urine. The following day no examination was made. 
A.M. A.M. 
h m h m oz. Spec.gr. Total carb. of sodarequired. 
Total quantity from 7 30 to 7 30 the next day =45 1026*7=4*82 grains 
rabout 3*89 measures of 
=i acid, per 1000 grs. of 
I urine. 
The conclusions from these experiments are, — 
I. As regards the variations of the acidity of the urine for three days on mixed 
diet. The acidity soon after food was found to decrease, and to attain its lowest 
limit from three to five hours after breakfast and dinner ; sooner, however, after 
breakfast than after dinner. The acidity then gradually increased, and attained its 
highest limit just before food. Once previous to breakfast, the urine was found more 
acid an hour before breakfast than it was immediately before food. 
If no food was taken the acidity of the urine did not decrease, but remained nearly 
the same for twelve hours. It fell immediately after food was taken. 
II. As to the influence of animal and vegetable food. 
When animal food only was taken, the diminution of the acidity after food was 
more marked and more lasting, than when a mixed diet was taken ; and the acidity 
before food rose rather higher with a mixed diet than it did with animal food. 
