250 
DR. BENCE JONES ON THE DEPOSIT 
Hence no conclusion can be drawn regarding the effect of exercise on the excretion 
of uric acid. The influence of food lasts so long in increasing the amount of urates 
that no results regarding exercise could be obtained; experiment (14) is no positive 
proof of the increase or diminution of the uric acid by exercise. 
The three following days the total amount of uric acid excreted in twenty-four 
hours was determined. The breakfast and dinner were of meat and bread, coffee, 
wine and water : the same each day. 
Uric acid per 
Uric acid. Quantity 1000 grs. 
gr. Spec, gr. of urine, of urine. 
(16.) Total quantity from 7^ 30”“ A.M. to 7^ 30“ a.m.=5’9 1022'4=46^I 0*29 gr. 
(17.) The following day. Total quantity . . =7’7 ]027'l=35f§ 0-48 
(18.) The following day. Total quantity . . =7*0 1023'8 = 44§ 0-36 
In the course of the following three dqys nine drachms of dilute sulphuric acid 
were taken. The food was the same as before. 
Uric acid per 
Quantity 1000 grs. 
Spec. gr. of urine, of urine. 
1026-2 = 40g 0-41 gr. 
1020*3 = 54g 0-27 
1028'6=:40g 0-56 
( 1 9.) Total quantity from 7^‘ 30“ a.m. to 7^ a.m. 
(20.) The following day, total quantity . . 
(21.) Thick from urates, the following day, quantity 
The conclusions from these experiments are, — 
I. As regards the variations of the acidity and uric acid when mixed diet was taken. 
Uric acid. 
gr- 
.=7-3 
. = 6-5 
:9-9 
Per 1000 grs. of urine. 
Spec. gr. 
0-048 gr. 
1026-3 
0-17 gr. 
1023-1 
0-39 gr. 
1021-0 
0*92 gr. 
1031-1 
. 23-37 measures 
1026-7 
. 30-24 measures 
1024-9 
7-30 measures 
1025-1 
. 26-21 measures 
1030-0 
The uric acid varies before food from 
The uric acid varies before food to . 
It varies after food from .... 
It varies after food to . ... 
The acidity varies before food from . 
The acidity varies before food to . . 
It varies after food from .... 
It varies after food to 
II. As to the influence of vegetable and animal food and exercise. 
When vegetable food only was taken the uric acid was highest after food. 
Per 1000 grs. of urine. 
Being at most TOl gr. 
Then the acidity was 12‘67 measures 
The uric acid was least before food, being at least 0'049 gr. 
Then the acidity was 26'36 measures 
When animal food only was taken the uric acid was highest after food. 
Being at most T022 gr. 
Then the acidity was 18'48 measures 
The lowest uric acid was before food, being at least 0-049 gr. 
Then the acidity was 21-46 measures. 
Spec. gr. 
1025-6 
1024-0 
1027-8 
1024-8 
