722 
PROFESSOR HARLEY ON THE INFLUENCE OF 
Arsenic. 
In testing the action of arsenic, as in the case of corrosive sublimate, non-defihrinated 
freshly-drawn arterial blood was employed, and the quantity of air with which it was 
enclosed also amounted to 150 per cent. In this instance, however, dog’s instead of 
calf’s blood was employed ; and in order to give to the experiment all possible exacti- 
tude, while one of the portions of blood had 120 drops of a saturated aqueous solution 
(by boiling) of arsenious acid added to it, the other was treated to a similar amount of 
distilled water. In all other respects they were treated precisely alike, both before and 
after the twenty-four hours’ action. 
Gas from non-defibrinated fresh dog’s blood plus 120 drops of distilled water, twenty- 
four hours’ action with 150 per cent, of atmospheric air : — 
No. 67.- 
Oxygen . . . 
Carbonic acid . 
Nitrogen . . . 
-In 100 parts of air. 
20-376 
0-981J 
78-643 
l-Total 
oxygen 21-357 
Gas from dog’s blood plus arsenious acid, twenty-four hours’ action with 150 per cent, 
of atmospheric air: — 
No. 68. — In 100 parts of air. 
Oxygen . . 
Carbonic acid 
Nitrogen . . 
iTotal oxygen 21-538 
0-268 J 
78-562 
It is thus seen that arsenious acid is one of those substances which retard the trans- 
formation of the constituents of the blood on which the absorption of oxygen and exha- 
lation of carbonic acid in the respiratory process depend. 
Oxygen. 
Carbonic acid. 
Nitrogen. 
Total oxygen. 
In 100 parts of air from pure dog’s blood ... 
20*376 
0*981 
78*643 
21*357 
Ditto plus arsenic 
21*270 
0*268 
78*562 
21*538 
Pure atmospheric air 
20*960 
0*002 
79*038 
20*962 
A precisely similar result was obtained with defibrinated calf’s blood. 
Tartrate of Antimony. 
A quantity of well-defibrinated sheep’s blood, after being thoroughly saturated with 
oxygen, was divided into several portions, and while one was left in its normal condition, 
0*02 gramme of tartrate of antimony was added to another (the quantity of blood 
employed in each case was 62 grammes). The blood was treated in the usual manner, 
in receivers with 100 per cent, of air, during twenty-four hours. 
