OF THE BARK OF ERYTHROPHLEUM GTJINENSE. 
651 
The rise of pressure in this experiment was greater than in any other in which the 
cord had not been divided. This seemed to us so extraordinary that we thought at first 
that the cord had not been properly divided ; but a careful dissection made immediately 
after death showed us that the division was complete. A year or two ago this result 
would have been regarded as a proof that the drug acts on the vessels themselves ; but 
recent researches having shown that much more importance must be attributed to vaso- 
motor centres in the cord and in the periphery than was previously done, we cannot 
say whether the drug acts on these centres or on the walls of the vessels themselves. 
The non-contraction of the vessels of the frog’s web would indicate that the action of 
the drug is rather on nervous centres in the cord or neighbourhood of the vessels than 
on the vascular walls. 
In order to exclude all centres except those in the periphery, Experiment XLIII. was 
performed. 
Experiment XLIII. 
The sympathetic cord was divided on the right side of the neck of a rabbit and the 
animal allowed to come out of the chloroform anaesthesia. The ear of the right side 
was deeply injected while the left ear was very moderately filled with blood. A dose 
of casca was then administered. The vessels of both ears became pale, those of the 
right ear equally so with those of the other. 
Vessels affected by the Drug. 
The vessels by which the blood-pressure in the body is chiefly regulated are those of 
the intestines, those of the skin and muscles being very much less under the influence 
MDCCC LXXVII. 4 Z 
