504 
MR, J. PRIESTLEY ON THE PHYSIOLOGICAL ACTION OE VANADIUM. 
h. m. 
3 0. The animal has exhibited no fresh symptoms ; it is, however, now breathing 
more rapidly (33’3 in 10 seconds), as if much exhausted. It is quite sensitive. 
3 45. Breathes very heavily, with a gurgling noise in the throat. 
3 50. No paralysis, but great weakness and evident pain. 
4 5. Breathing 76 per minute (12-6 in 10 seconds) and irregular. 
4 45. Creeps along, evidently very weak. 
5 10. Still sensitive; on touching the eyeball the lid moved languidly. 
5 30. Gurgling noise in throat ; struggles as if in great pain ; drops of serous fluid 
exude from the nose ; asphyxia. Eyes prominent. Gasps at intervals of 
5-6 seconds. Heart has ceased to beat. Serous exudation from nose and 
mouth. 
5 o5. Head. 
Post mortem Examination. 
Muscles contract on direct stimulation. 
Blood dark-coloured, asphyxial. 
6 5. Heart contracts on stimulation ; right side distended. 
General visceral congestion. 
Liver pale, but otherwise normal. 
Lungs congested, mottled with purple, the upper lobes more than the 
lower, and the left lung more than the right. 
Stomach congested internally, especially near the smaller curvature and 
vertebral aspect, becoming less so towards the cardiac end, where, however, 
there is one piece of arborescent congestion apparent. There is another such 
patch on the abdominal aspect (internal surface) of the same viscus. 
(Esophagus hardly congested. 
Duodenum congested in patches internally at the free border, especially 
towards the lower end. 
Great congestion of the free border of the small intestine, becoming more 
extensive as we descend. Towards its lower end the small intestine is filled 
with a brown opaque mucus. 
Large intestine not nearly so much congested as small. Rectum partakes 
of the characters of the rest of the large intestine. 
Bladder contracted and not congested. 
Uterus slightly congested externally, but not so internally. 
Kidney congested internally. 
From this experiment we learn that 25 milligrammes of V 2 0 5 produced death in 8f 
hours, and that symptoms of poisoning began to appear within 20 minutes. The 
symptoms were convulsive twitchings, partial and temporary paralysis, abdominal pain, 
rapid respiration. No importance can be attached to the apparent dilatation of the 
pupils, as it may have been due to the shade of the box. After death there were very 
