ME. J. PEIESTLEY ON THE PHYSIOLOGICAL ACTION OP VANADIUM. 
509 
in 10 minutes. Symptoms developed within 2 minutes of injection, and confirmed 
those of the preceding experiment. 
On Dogs. 
Exp. XXVI.— December 10, 1874. 
The dog was a small, rough, young terrier ; it had been used five days before 
in an experiment in which 100 milligrammes (1) of V 2 0 5 had been 
injected (in the form of neutral sodium vanadate) into the right external 
jugular vein without producing death. It had apparently completely 
recovered. 
Dose 10 cub. centims. of the 5 per cent, solution (500 milligrammes V 2 0 5 ), 
injected under the skin of the back. 
h. m. 
11 50. Injection complete ; dog slightly sick. 
12 5. Much terrified ; slight diarrhoea ; vomits a stringy mucus ; walks quite well. 
12 20. Vomited more mucus of a tenacious ropy nature. 
12 50. Salivated. Discharge of watery matter from rectum. 
1 15. Watery discharge ‘per rectum continues, together with a quantity of light, 
loose faeces. 
1 40. Breathing irregular. 
2 0. Attempts to vomit ineffectually; breathing rather laboured and irregular; 
watery discharge from rectum continues. 
2 40. Again sick ; vomited more stringy mucus. Discharge from rectum still con- 
tinues. 
3 25. Symptoms as before ; breathing irregular and laboured ; watery discharge from 
rectum as before. 
3 40. No paralysis or convulsions have as yet been noticed ; breathing heavy. 
4 30. Still salivated. 
5 15. Appears unable longer to support itself, and has fallen over on to its side ; 
breathing short and irregular ; quite conscious. 
5 25. Raised itself and sat up, but with great difficulty ; sways about as if weak and 
unable to hold itself steadily upright. 
5 30. Lies down again ; quite conscious. 
6 0. Region around the anus covered with a sanguineous watery matter which has 
issued from it during the afternoon. 
6 30. Quite conscious. 
7 0. Quite conscious. 
7 10. Breathes heavily and at short intervals. 
8 0. Conscious; breathing slight. 
8 40. Eyeball but slightly sensitive. 
9 40. Still breathing. 
10 55. Dead. 
