524 ME. J. PEIESTLEY ON THE PHYSIOLOGICAL ACTION OF VANADIUM. 
From this experiment we learn that the blood-pressure declined steadily until the 
death of the rabbit, with the exception that once or twice it tended to regain its former 
level, the rise being accompanied sometimes by violent movements of the muscles. 
On one occasion the rise and the muscular movements were both violent and sudden 
and simultaneous ; but previously the convulsions or muscular movements preceded by 
about 15 seconds the rise, which was slow and accompanied by as gradual a fall. 
Although the record of the pulse is not very exact, as the rate of rotation of the cylinder 
was not checked, we can make out a decline in the number of heart-beats per 10 seconds, 
which is almost constant. The pulse, moreover, became at first much more marked as 
well as slower. 
Exp. XLV.— May 13, 1874. 
Rabbit (male). — Weight 1958 grms. 
Dose 5 cub. centims. of the 5 per cent, solution (250 milli- 
grammes V 2 0 5 ), injected under the skin. 
Time. 
Mean B. 
Pulse in 
10 seconds. 
Remarks. 
Xymographic cannula in left carotid artery ; tracheal can- 
h. m. s. 
nula fixed for simultaneous respiration-tracing (see 
p. 537). 
1 41 0 
128 
38 
Normals prior to injection ; respiration-curves are shown ; 
Excursion of pen at each pulse =2 millims. 
1 47 0 
113 
41 
Injection finished ; excursion of pen much less ( = 1 millim.) 
at each pulse and irregular. 
1 49 0 
1 49 30 
116 
98 
39 1 
30-33 J 
Irregular pulse ; composed of alternate long and short beats. 
1 50 0 
29-30 
Pulsations irregular ; irregularities in line of blood-pressure 
due to struggles ; respiration-curves have disappeared. 
1 52 30 
96-5 
36-38 
Pulsations regular but slight. 
1 53 45 
84 
23 
1 54 30 
90] 
1 54 45 
94 
33-34 
Pulse irregular and feeble. 
1 55 0 
90 
1 56 30 
83 
27-28 
1 58 0 
30 
Pulse alternately long and short. 
1 58 30 
77 
20 
Pulse marked; excursion of pen =2— 3 millims. 
2 0 0 
74 
28 
Pulse regular but feeble. 
2 1 30 
62 
19-20 
Pulse deeper but regular. 
2 2 30 
67 
22 
2 3 30 
50 
15 
2 6 0 
36-5 
22-16 
2 8 30 
32 
17 
Pulse feeble but regular. 
2 9 30 
36-i 
5 
15 
2 10 30, 
38 
13 
Pulse feeble but regular. At this point a clot formed in 
the cannula and was removed. 
2 12 45 
621 
18} 
The line indicating mean blood-pressure now commenced 
2 12 50 
66/ 
to describe long, sweeping curves; pulse deep and 
2 13 0 
2 13 10 
52 
62" 
i 
J 
regular. 
2 13 20 
48 
20 
Pulse deep and regular ; sweeping curves of B. P. line. 
2 13 30 
53 I 
1 
2 14 0 
30 
10 
Pulsations deep, irregular and jerky. 
