ME. J. PRIESTLEY ON THE PHYSIOLOGICAL ACTION OF VANADIUM:. 527 
Exp. XLVII.— June 15, 1874. 
Babbit. — Weight 2430 grms. 
Dose 1 cub. centim. of the 5 per cent, solution (50 milligrammes 
V 2 0 5 ), injected into the right external jugular vein. 
Time. 
Mean B. P. 
Pulse in 
10 seconds. 
Remarks. 
h. m. s. 
12 10 5 
116 
49 
Kymographic cannula inserted into left carotid artery. 
Cannula in vein for injection. Cannula in trachea for 
simultaneous respiration tracing (see p. 538). 
Normals prior to injection. 
12 11 30 
117 
45 
Normals prior to injection. Respiration- curves well shown. 
12 14 55 
117 
49 
Commenced to inject. About 10 seconds after the B. P. 
12 15 10 
128 
47 
commenced to rise. 
Injection complete. Pulse changed suddenly. 
12 15 15 
22 
The B. P. sank more quickly than it rose ; it sank to 70 
12 15 20 
70 
millims., and afterwards began to rise again, reaching a 
12 15 25 
95 
14 
height of 95 millims., owing to the rabbit’s struggles. 
12 15 40 
48 
12 
Respiration-curves disappeared. 
Pulse regular and deep. 
12 16 15 
36 
12 
12 16 45 
31 
14 
Pulse shallower. 
12 16 55 
The B. P. rose several times very suddenly, owing to the 
struggles of the rabbit. Twice it attained a height of 
61 millims. 
The rabbit began again to struggle ; it appeared to be con- 
12 17 40 
12 18 20 
e>i 
31 
10-14 
12 18 45 
22 
5-6 
vulsed, exhibiting tonic spasms of the lower limbs. The 
eye became insensitive and the pupil dilated. The B. P. 
rose and fell irregularly. 
The B. P. became steady and the pulse regular, long, and 
12 20 20 
10 
shallow. 
Respiration in gasps ; pulse very feeble. 
12 21 30 
14 
Heart ceased to beat. 
12 22 0 
9 
Dead. 
In this experiment, with the exception of certain disturbances occasioned by the 
struggles of the animal, the variations in the character of the blood-pressure and the 
pulse resemble exactly those in the preceding one. 
In the next two experiments it was desired to see the effects of poisoning by vanadium 
after section of both nervi vagi. 
