528 ME. J. PEIESTLEY ON THE PHYSIOLOGICAL ACTION OE VANADIUM. 
Exp. XLYIIL— February 19, 1874. 
Rabbit. — Weight 1761 grms. 
Dose 5 cub. centims. of the 5 per cent, solution (250 milligrammes 
V 2 0 5 ), injected under the skin. 
Time. 
Mean B. P. 
Pulse in 
10 seconds. 
Remarks. 
h. m. 
S. 
4 21 
0 
112 
50-57 
Normals after insertion of cannula into left carotid artery 
for kymographic tracing and exposure of both nervi vagi. 
Eespiration-curves are well shown ; pulse small. 
4 22 
0 
106 
Both vagi divided ; respiration-curves shown ; pulse small. 
4 22 
15 
136 
4 22 
30 
120 
52 
4 23 
0 
50-60 
4 28 38 
112 
60 
Injection commenced. 
4 29 
0 
116 
62 
Injection complete. Eespiration-curves shown. 
4 30 30 
102 
30 
No respiration-curves ; pulse small ; long sweeping curves 
described by the kymographic pen. 
4 30 
40 
120 
28 
Pulse dicrotic ; long sweeping curves of blood-pressure line 
as above. 
4 30 
55 
93 
4 31 
0 
116 
] 
4 31 
15 
86 
l 50 
f Eespiration-curves pretty well shown ; long sweeping 
4 31 
30 
105 
[ curves of line of blood-pressure. 
4 31 
40 
82 
J 
4 33 
0 
72 
26 
No respiration-curves. 
4 34 
10 
50 
30 
4 35 
0 
56 
32 
Eespiration-curves shown. 
4 36 
0 
48 
31 
Long sweeping curves, as above. 
4 36 
20 
40 
4 36 
25 
50 
Struggles of rabbit, and irregular rises and falls of blood- 
pressure. 
4 37 
0 
62 
32 
Pulse regular. 
4 37 
25 
42 
32 
Pulse very faint. At this point there occurred numerous 
irregular rises and falls of hlood-pressure coincident 
with respiration. Pulse cannot he counted. 
4 38 
0 
62 
32 
Pulse regular. 
4 38 
20 
38 
Pulse slight but regular. 
4 44 
0 
28 
A delay had been occasioned by winding up the clockwork 
of the revolving cylinder, which had run out. Con- 
vulsions. 
4 44 
15 
23 
Opisthotonic convulsions ; pulse cannot be counted ; blood- 
pressure very irregular, exhibiting sudden rises and falls. 
4 45 
0 
0 
Dead. 
The symptoms exhibited by this rabbit resemble in general those of the rabbit in 
Experiment XLY., where the same dose was injected in a similar manner without previous 
section of the vagi. Here, as there, the blood-pressure commenced to sink after poison- 
ing ; but at intervals it tended to regain its former height (even exceeding it at one 
moment) by gradual rises succeeded by gradual falls, the results of which are recorded 
on the recording cylinder as long, sweeping curves. The oscillations of blood-pressure, 
normally coincident with respiration, disappeared and reappeared several times in this 
experiment — a circumstance which was not noticed in Experiment XLY. In addition 
to these regular variations of blood-pressure, there occurred several jerky irregularities. 
