ME. J. PEIESTLET ON THE PHYSIOLOGICAL ACTION OF VANADIUM. 529 
due, apparently, in most cases, to struggles or convulsions. With respect to the pulse 
the comparison of the two experiments holds good also, when we take into consideration 
that the rapidity is, in general , greater in the case of the rabbit with divided vagi. 
Section of the vagi in rabbits does not at once cause the pulse to increase in rapidity. 
Bearing in mind, therefore, the fact that the full effect of division would occur after the 
injection of vanadium, we can see that there was a gradual decline of rapidity, marked, 
as we have noticed in preceding cases, by short periods of acceleration. For the rest, 
the animal exhibited the usual convulsions prior to death. 
Exp. XLIX.— June 24, 1875. 
Rabbit. — Weight 1315 grms. 
Dose "75 cub. centim. of the 5 percent, solution (37‘5 milligrammes 
V 2 0 5 ), injected into the right external jugular vein. 
Time. 
Mean B. P. 
Pulse in 
10 seconds. 
Remarks. 
Both vagi exposed ; kymographic cannula inserted into the 
left carotid artery ; cannula inserted into the right ex- 
h. m. s. 
ternal jugular vein for injection. 
4 45 0 
101 
Normal blood-pressure. 
4 47 10 
101 
42 
Normals prior to injection. Eespiration-curves pretty well 
shown. 
4 47 20 
43 
Left vagus divided. Blood-pressure rises. Eespiration- 
curves well shown. 
4 47 35 
108 
4 47 40 
48 
Eight vagus divided ; hlood-pressure rises. 
4 48 0 
142 
41 
Eahhit struggles and cries ; irregularities of blood-pressure 
A 4Q 1 ft 
f US 1 
AQ 
follow. Noise in throat of rabbit, due to paralysis of 
jlv 
1 io8 ; 
laryngeal muscles. Eespirations 4 in 10 seconds. 
4 50 5 
105 
53 
Injection commenced. Within 7 seconds of commencement 
4 50 10 
49 
the blood-pressure began to rise, reaching a maximum 
4 50 15 
113 
46 
of 113 millims. 
4 50 20 
Injection complete. The blood-pressure fell suddenly, hut 
4 50 30 
r 7oi 
24 
rose again to 82 millims. The pulse changed suddenly 
1 82 J 
in character, becoming at first shallow and rapid, then 
deep and irregular ; the respiration-curves disappeared. 
4 51 0 
27 
Pulse rather more regular. 
4 51 15 
56 
23 
Eespiration-curves have reappeared, and seem normal. 
Pulse seems composed of alternately short and long 
heats. 
4 51 20 
The rabbit here commence^, to struggle, and continued to 
do so for two minutes, causing great disturbance in the 
hlood-pressure and obscuring the pulse; respiration- 
curves have disappeared again. 
4 53 10 
24 
10-11 
Pulse very irregular. Further struggles, forcing the blood- 
pressure up. 
4 54 30 
18 
11-12 
Pulse more regular. Eye insensitive. 
4 55 40 
12 
10 
Eespirations seem to have ceased. 
4 59 0 
6 
3-4 
Pulse remarkably shallow and long. 
4 59 40 
5 
4 
Death. 
A comparison of this experiment with one (say Exp. XLVI.) in which the conditions 
MDCCCLXXVI. 4 D 
