ME. J. PEIESTLET ON THE PHYSIOLOGICAL ACTION OE VANADIUM. 
545 
h. m. 
3 56. Lies in a curious posture, with its arms folded beneath it. Membrange nictitantes 
half closed. Lower jaw beginning to droop. On being turned over on to its 
back it does not attempt to recover. No throat-movements of respiration. 
On pinching each foot the corresponding leg moves, and to an equal extent 
in each case. 
4 0. Moves spontaneously towards a dark corner of the bell -jar. 
4 3. On stirring the bell-jar the frog respired, and jumped. 
4 10. On pinching either foot it moved both legs with equal vigour. The frog leaped 
away after having its poisoned leg pinched. Lies on belly. 
4 12. Spontaneous movements. 
The frog was taken from the bell-jar and both feet immersed in a 2 per cent, 
solution of H 2 S0 4 ; both legs moved, but the poisoned one first by a second 
or two. A 4 per cent, solution of H 2 S0 4 was taken, and at 
4 32. The frog’s feet were immersed in it : no movements occurred after they had 
remained in for 50 seconds. 
4 34. No movements occur on pinching all over the body and limbs. 
4 40. Decapitated. Irritated the exposed end of the cord ; movements in the arms 
and lower jaw (which had been allowed to remain) with the secondary coil at 8. 
4 44. Passed the electrodes down behind the cord for about ^ an inch (with care, so 
as not to injure the cord) ; movements followed, on passing a current, when 
the secondary coil stood at 9. 
4 50. Removed the back of the 5th (or 6th) vertebra as carefully as possible ; inserted 
the electrodes into the cord : movements followed with the secondary coil 
at 11. 
4 53. Removed the back of the vertebral arch next below, and inserted the electrodes 
into the cord ; movements followed in the abdominal and thigh-muscles 
with the secondary coil at 11. 
4 55. Removed the back of the arch next below; extension of both legs occurred on 
passing a current with the secondary coil at 11. 
5 0. Both sciatics exposed and placed on the electrodes below (as well as above) the 
level of the ligature on the right femoral artery ; equal movements of both 
calves followed with the secondary coil at 21. 
5 4. The muscles of both legs were irritated directly, and about equal extent of 
movement occurred in both poisoned and non-poisoned leg with the secondary 
coil at 10.5. 
From this experiment we deduce the following : — At a time when the vanadium salt 
had undoubtedly commenced to produce nervous symptoms no indications of any 
affection of sensory nerves in the poisoned limb could be detected ; at least, the indica- 
tions given by the poisoned limb were exactly such as were given by the non-poisoned 
limb. There was, however, distinct impairment of reflex excitability, as shown by the 
MDCCCLXXVI. 4 F 
