DK. E. KLEIN ON THE SMALLPOX OE SHEEP. 
217 
They were excised as 
follows : — 
No. 1. 
January 
20 
o 
5 ? 
55 
22 
„ 3. 
55 
26 
„ 4. 
,5 
29 
„ 5. 
February 
1 
„ 6 . 
55 
1 . 
One had disappeared. 
Only Nos. 4, 5, and 6 showed traces of the formation of pustules. 
The relation of the temperature of the animal was as follows : — 
O O 
January 15 . . 
. 39-2 C. 
January 22 
. 41 C. 
„ 16 . . 
. 39-2 
„ 23 
. 40-7 
„ 17 . . 
. 39-3 
„ 24 
. 41-1 
„ 18 . . 
. 39-5 
„ 25 
. 40-8 
„ 19 . . 
. 40-3 
„ 26 
. 40-5 
„ 20 . . 
. 40-8 
„ 27 
. 41 
„ 21 . . 
. 41-2 
„ 28 
. 40-8 
The temperature remained over 40° C. until the 1st of February, when the animal 
died. It had very extensive suppuration of the part from which the pocks had been 
cut out, and these extensive suppurations may easily have caused the abnormally high 
temperature after January 24. On a post-mortem examination being made, the lungs, 
liver, and peritoneum were found to contain numerous nodules of a parasitic nature, 
which of course stand in no relation to the inoculated disease. 
Experiment 3. — On the 10th of March, 1874, lymph sent by Professor Cohn, of 
Breslau, diluted with ten times its bulk of thoroughly boiled ^ per cent, saline solution, 
was used for inoculating a healthy sheep ; four punctures were made in the skin of the 
right and five in that of the left ear-lobe. On the 16th of March most of the pocks 
had made their appearance ; they were in all respects similar to those described in 
experiments 1 and 2. They enlarged in size until March 20, and most of them became 
pale and depressed in the centre, thickened and red in the periphery. Commencing 
from the 24th they all showed suppuration and sloughing. 
The course of temperature was as under : — 
March 11 . . 
. 39-2 C. 
March 18 
. . . 40-5 C. 
55 
12 . . 
. 39-3 
„ 19 
. . . 40-4 
55 
13 . . 
. 39-2 
„ 20 
... 40 
55 
14 . . . 
, 39-3 
„ 21 
. . . 39-8 
55 
15 . . , 
. 39-5 
„ 22 
. . . 39-8 
55 
16 . . , 
. 40-5 
„ 23 
. . . 39-6 
55 
17 . . , 
. 40-9 
„ 24 
. . . 39-5 
