DR. E. KLEIN ON THE SMALLPOX OF SHEEP. 
249 
or filamentous substance may be observed in some of the superficial vacuo- 
lated epithelial cells, which is probably connected with the fungus found 
in the pustules (see figs. 18 & 19). 
PLATE 29. 
Fig. 16. Vertical section of rete Malpighiiof a secondary pustule — that is, one forming 
part of the general eruption. (Oc. 3, obj. 7.) The rete Malpighii is thickened, 
and in the middle layers single epithelial cells are seen being converted into 
vesicles. 
A. Horny layer. 
B. Deep layer of the rete Malpighii. In both layers of the rete many of 
the nuclei of the epithelial cells are changed into well-defined vesicles. 
C. Vesicles containing the mycelium of the Oidium - like fungus. 
D. Vesicle in which the matrix of the mycelium has been stained with 
carmine. 
Fig. 17. Part of the contents of the pustule represented in fig. 16. (Oc. 3, obj. 10, 
immersion.) The OidiumASke, fungus seen in the previous figure is imbedded 
in a finely granular substance (coagulated plasma). 
Figs. 18 (PI. 29) & 19 (PI. 30) are both preparations from a primary pustule, showing 
the identity of the fungus found in primary and secondary pustules. (Oc. 3, 
obj. 10, immersion.) 
[The research to which the present paper relates has been made as one of the series 
of scientific investigations which the Lords of the Council are pleased to authorize me 
to have conducted at their expense in aid of Pathology and Medicine. 
The paper itself, being of the nature of a Report for the Lords of the Council, may 
probably appear entirely or in part as a Parliamentary Publication ; but the immediate 
interest of the facts makes me think that the Royal Society will be glad to be at once 
possessed of them ; and I therefore avail myself of their Lordships’ permission to com- 
municate the paper to the Society. — John Simon.] 
