442 
DE. D. EEEEIEE ON THE BEAIN OE MONKEYS. 
The angle of the month was 
Kg. 7. 
no diminution of sensation or voluntary motion. It closely watched flies buzzing about, 
and frequently made attempts to catch them. 
Towards the afternoon it began to suffer from choreic spasms of the left angle of the 
mouth and of the left hand. There was no loss of consciousness. The animal was 
apparently annoyed by the spasmodic action of its mouth, and frequently endeavoured 
to still them by holding its mouth with the other hand. 
Towards the close of the day the spasms frequently repeated, became more intense, 
and exhibited an epileptiform nature, the convulsions of the left side of the body 
becoming general. 
This state continued till 
June 23rd . — Left hemiplegia had manifested itself, 
drawn to the right, the left cheek-pouch was 
flaccid and full of food, there was almost total 
paralysis of the left arm, and partial paralysis 
of the left leg. The pupils were equal, and 
there was no paralysis of the left eyelids appa- 
rently. The animal still maintained an intel- 
ligent aspect, but seemed disinclined to move 
on account of the powerlessness of its left side. 
June 24 th . — Hemiplegia is complete on the left 
side, hand, foot, and face. The animal moved by 
means of its left limbs, dragging the right after it. 
The animal died from exhaustion on the 27th. 
Post mortem Examination . — The whole of the 
exposed part of the brain was in a state of 
softening and suppuration, projecting through 
the opening of the skull. 
The extent is indicated in figure 7. 
Eig. 7 represents the right hemisphere of 
the Tbrain of the monkey. The shaded part 
indicates the extent of destruction of the grey 
matter in Experiment IY. 
c=the fissure of Kolando. 
d = the postero-parietal lobule or upper end 
of the ascending parietal convolution. 
e = the ascending frontal convolution. 
The brain otherwise was normal. The softening was confined to the surface of the 
hemisphere, and did not extend to the ganglia, which were normal. 
In this experiment we have a general affection of the whole of the motor region of 
the right hemisphere, beginning with inflammatory irritation, which showed itself in 
choreic spasms passing into general epileptiform convulsions, and ending ultimately, 
as softening advanced, in complete left hemiplegia. 
This result followed destruction of the cortical motor centres alone. 
Experiment V. 
January 5th, 1875. — A macaque of large size was placed under the influence of 
chloroform, and the ascending frontal, ascending parietal, and postero-parietal convolu- 
tions of the left hemisphere exposed. 
Electrical irritation was applied, and the movements already related as following 
