466 
DR. D. PERRIER ON THE BRAIN OF MONKEYS. 
No difference observed in the animal when again tested at 7 p.m. 
February 11th . — 10 a.m. The animal looks much as before. The wound is suppu- 
rating freely. Can see and hear, and move about. Takes every thing offered to it in its 
left hand. Reaction to hot iron still continues on both sides. A sore on its right 
foot seems to cause it great trouble, as it is continually biting and scratching it. 
February 12tli . — 10 a.m. The animal ate and drank as before. There appeared to be 
slight twitching of the right side of the body. Reaction to heat still observed on both 
sides. 
10.45 a.m. The animal had again a return of the twitching of its right side. The 
animal was quite conscious, and did not fall. After a few minutes the animal walked 
back to the fire, whence it had been removed for observation. It was now seen to drag 
its right limbs somewhat. 
11.40 a.m. In climbing in its cage seems to have great hesitation in using the right 
hand. When taken out had a slight return of the twitching. When it had ceased 
some food was placed in its right hand. Failed to grasp it, but took it with its left 
hand, raised it to its mouth and ate. 
4 p.m. Still continues to drag its right limbs in walking, and cannot grasp with the 
right hand. There is marked diminution of reaction on the right side, as compared 
with the left, when a hot iron was applied. 
After this there was a return of the spasmodic twitching of the right side. 
In the interval of the fits the right leg was again tested with the hot iron, and 
reaction seemed to have entirely disappeared, while reaction was active when the stimulus 
was applied to the left. 
Towards evening the animal began to exhibit symptoms of basilar meningitis, 
suffering from frequent convulsive seizures. It became comatose, and died in convul- 
sions on February 13. 
Post mortem Examination (February 13th, 10.30 a.m.). — The exposed posterior extre- 
mity of the left occipital lobe was fungating. The dura mater stripped easily from the 
surface of the brain ; but the vessels of the pia mater were injected on the left hemi- 
sphere, particularly on the postero-parietal region. 
The course of the wire was easily traced by the sinus it had caused, and by a line 
joining the points of entrance and exit. After penetrating the occipital lobe it had 
ploughed a furrow on the upper extremity of the uncinate gyrus (see fig. 22), and then, 
instead of following the inner aspect of the temporo-sphenoidal lobe, had made its way 
horizontally outwards through the lobe, and emerged on the outer aspect at the extre- 
mity of the superior temporo-sphenoidal fissure (see fig. 23). On examination of the 
brain after hardening in spirit, it was found that softening had extended from the track 
of the wire, and that the hippocampus was in great measure softened down and dis- 
organized. 
In addition to these appearances there were signs of inflammation of the membranes 
at the base of the brain, on the pons, and anterior surface of the medulla. The left 
