N. O. APOCYNACE/E. 
803 
of Selmis's Ptomaines (Fiuoshi) ; statements of diffrent observers concerning 
Oleandrine, Neriin, Ncriodorin, &c., are conflicting ; see Leuknowsky, Rep. 
Ohim. Appliq., Ill, 77 ; Schmiedoberg Archiv., Exp. Pathol., XVI, 151 ; Greenish, 
Pharrn. J„ Trans., 3rd Ser., XI., 878, and others] Amorphous, yellow, resinous, 
biiter, poisonous. After heating to 240“ C. it is no longer soluble in alcohol 
or water. Melting point above 56° C. with crystalline sublimate. Soluble in 
water, Betelli ; alcohol, ether, chlorofrm and fatty oils. 
Ncriodorin scarcely soluble in water or ether, not soluble in benzene or 
petroleum ether. For further information regarding the precipitants, see 
Sohn. 
2. Neriin has all the properties of Digitalin and possibly identical there- 
with. i 
3. Nerianthin bears similar resemblance to Digitalin. 
4. Rosaginin . — A Glucoside (E. Picszczck). Amorphous, Archiv. Pharrn., 
1890,852 ; poisonous; action like Strychnine. Soluble in alcohol; not in 
water, ether, chlorofrom or petroleum ethers. For farther tests, see Sohn. 
The presence of the Glucoside Rosaginin would seem to account for tetanic 
symptoms noticed in two cases reported in the Indian Medical Gazette of 
1866. 
DrcgendorfE recognizes Oleandrine as the alkaloid found in the plant, but 
says he is not familiar with it and refers the reader to the researches of 
Leukowsby.* Dymock, in referring to the researches of Leukowsky says that 
the latter recognises in the leaves of oleander the preseiice of two alkaloids — 
namely, Oleandrine and Pseudo-curarine. Dymock further quotes the resear- 
ches of Schmiedeberg, which, in view of the quotation from Sohn given above, 
referring to the difference of opinion as regards the nature of the true 
alkaloid, may well be repeated here. “ Schmiedeberg (1883), who considers 
Oleandrine to he a glucoside, found in the leaves two other glucosides— 
Neriin and Neriunline : ho cosiders Neriine to be identical with Digitaleitie.”f 
Greenish recognizes two bitter principles in the bark, Ncriodorein and 
Ncriodorin, which, he says, are closely allied non-nitrogenous substances, 
probably glucosides, both possessing the properties of powerful cardiac 
poisons. In the bark, he says, there are crystals of calcium oxalate. (Year 
Book of Pharmacy', p. 154, 1S81). 
763 . Aganosma caryophyllata, G. Don., h.f.b.i., 
hi. 664 . 
Habitat : — Lower Bengal, Monghyr ; common on rocks at 
Risikund ; Dekkan Peninsula ; frequent on the Veligonda Hills 
of Cuddapah. 
A large, evergreen climber. Stem very stout. Shoots 
pubescent. Leaves 4-5 by 2-2-|in., ovate or elliptic, coriaceous, 
acute, obtuse or acuminate, glabrous or tomentose beneath, 
* Plant Analysis transtated by Greenish, p. 204, 1884. 
t Pharmacographia Indica, p. 401, Vol. II, 1891. 
