J2 
N. (). ASGLfcll’UDE.'K. 
817 
(acetate, needles, m, 222’), oxidized by Cr0 3 in HOAc to akundaric acid, isolated 
as the silver salt, C 3a H b ,,0 3 Ag, faintly green, amorphous. Sapon. of (C) gave 
mudurol (E), C 80 H 4S1 O., .hexagonal plates, m. 176° (acetate, needles, m. 195—6“), 
oxidized to muduric acid, amorphous, m. 225°, purified through the silver salt 
C 30 H 45 O 3 Ag, faintly green, amorphous, (it), (C), and thefir ales, gave color 
reactions very similar to those of cholesterol and phytosterol. A little (D) 
in 2 cc. CHC1 3 , tteated with 20 drops Ac 2 0 and 1 drop H 2 S0 4 , gave the usual 
violet-pink color, while (E) gave an intense blue. The resinous material evolv- 
ed NH, and amines when boiled with coned, aq. KOH, and was finally purified 
to a hard, brittle mass of the comp. C 34 H 47 0 12 N. (Chemical Abstracts, Jan. 10, 
1916 p. 41.) 
No crystalline derivative could bo, isolated from the guttapercha-like 
substance and no alkaloid could be isolated, although the yellow bitter 
principle gave the usual alkaloidal reactions. 
The following results were obtained from quantitative experiments on the 
powdered barbs : — 
Prom 
Prom 
Young Plants. 
Old Plants. 
Moisture 
121 
10-2 
Spirit extract 
15 
162 
Soluble in water 
7-2 
To 
Resins 
7‘8 
8-7 
Total Ash 
7-0 
12-2 
Sand 
2‘8 
7-2 
Pure Ash ... 
42 
5 0 
It will bo seen that the root-bark from the older plants has a higher per- 
centage of acrid and bitter resinous matters than that from the younger 
plants. In this connection attention should be drawn to a remark made some 
years ago by Moodeen Shorift of Madras. In the Supplement to the Pharmaco- 
poeia of l ndia, page 364, he reports that he found that the older the plant, 
the more active is the bark in its effects. (Hooper). 
The latex of 0. procera contains a rennet ferment, which, 
like those present in the fig, papaw, etc., coagulates boiled milk 
more rapidly than raw milk and is very resistent to heat. Its 
action is inhibited by mercuric chloride, but not by salts of the 
alkali metals. (J. Oh. S. A. II. p. 977.) 
Calotropis procera. — A new Heart Drug acting like Digitalis.— L. Lewin., 
Berlin. Arch. exp. Path. Pharm. 71, 142-56. The physiologically active sub- 
stance is found in the milky juice of the plant, in which it may be preserved 
for years without fermentation. The milk coagulates upon long standing or 
by the addition of ale. or Me., CO. D=1002 reacts all; The white, resin-like 
103 
