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PHARMA COGNOS Y. 
nally furrowed and wrinkled, 1'5 to 2 mm. in diameter, 
internodes from 2 - 5 to 6 - 5 cm. long. Leaves single or 
in unequal pairs, broadly ovate or somewhat elliptical, 
6 to 15 cm. long, 2 - 5 to 7 cm. broad; apex acuminate; 
base acute, somewhat unequal and tapering into the 
petiole ; margin entire ; upper surface dark green, 
glabrous, epidermis with distinct papillse ; under sur- 
face grayish green, slightly pubescent on the veins, 
epidermis distinctly sinuate, midrib dark brown, 
the veins of the first order diverging from it at 
angles of about 45° and running nearly parallel to 
near the margin ; petiole dark brown, 5 to 15 mm. long 
and semi-circular in cross section ; texture fragile. 
Flowers solitary, pedicel 1'5 to 2 cm. long; calyx 
deeply five-cleft, about 1 mm. long, outer surface 
slightly pubescent; corolla five-parted, about 2 mm. 
long, campanulate, yellowish purple; stamens five, 
distant, included; style somewhat exserted. Fruit, a 
superior berry, globular, dark green, 7 to 10 mm. in 
diameter, two-celled, many-seeded. Seeds campylot- 
ropous, somewhat reniform, flattened, light brown; 
testa finely pitted ; with a curved embryo imbedded in 
the endosperm. Odor distinct, heavy. Taste some- 
what disagreeable. 
Constituents. — Several alkaloids amounting to from 
0‘3 to 0‘7 per cent., of which hyoscyamine exists in 
largest proportion; the drug also contains atropine, 
formed from hyoscyamine, as well as other alkaloids; 
malic acid and calcium oxalate. 
STIiAMON 1 1 FOLIA (Stramonium Leaves). 
The leaves and flowering tops of Datura Stramonium 
(Fam. Solanacese), an annual herb probably indigenous 
to the region of the Caspian Sea, naturalized in waste 
places in Europe and North America, and cultivated 
