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PHARMA COGNOSY. 
to Eastern and Central North America. Boneset is 
collected in July and August and dried. 
Description. — Usually in more or lesss broken frag- 
ments. Stem cylindrical, somewhat quadrangular, flat- 
tened, about 3 mm. in diameter, longitudinally wrin- 
kled, tomentose ; internodes 5 to 8 cm. long. Leaf 
lanceolate, opposite, 10 to 20 cm. long, 2 to 4 cm. broad; 
apex acuminate; base connate-perfoliate; margin cre- 
nate-serrate ; upper surface dark green, midrib and 
veins depressed, reticulate, glabrous, except near the 
margin ; under surface yellowish or brownish green, 
midrib prominent, reticulate, very tomentose, with 
glistening yellow resin masses. Flowers in large 
terminal corymbs; beads ten to fifteen- flowered, about 
5 mm. long, receptacle flat; involucre light green, 
oblong, the scales imbricate, linear-lanceolate, hairy ; 
corolla five-toothed, whitish; anthers purplish, included; 
style deeply cleft, much exserted. Achenes five-angled; 
pappus smooth, consisting of a single row of about 
twenty rough bristles. Odor aromatic. Taste bitter. 
Constituents. — Volatile oil; a bitter, crystalline 
glucoside eupatorin ; resin ; a crystalline wax ; tannin ; 
gallic acid ; ash about 8 per cent. 
GRLNDELIA. 
The leaves and flowering tops of Grindelia robusta 
and Grindelia squarrosa (Fam. Compositse), perennial 
herbs indigenous to Western North America, G. robusta 
growing west of the Rocky Mountains and G. squar- 
rosa eastward therefrom as far as the Mississippi. 
Grindelia is collected in early summer when the leaves 
and tops are covered with a resinous exudation, and 
dried. 
Description. — Grindelia Robusta.— Stem cylindrical, 
lemon-yellow or rose-colored, 2 to 3 mm. in diameter, 
