Severin and Severin—Anatomical Studies of Cimbex. 47 
Appendix zusammenpresst und seinen Verschluss um so her- 
metischer macht, der so das Eindringen jeder Substanz, sei sie 
flussig oder nicht, dnrch die Endoffnung verhindert.” 
MID-IXTESTINE. 
Throughout the mid-intestine, the transversely folded wall 
is nearly uniform in structure and consists of a number of lay¬ 
ers which are, passing from within outward:—(1) a layer of 
cylindrical epithelial cells with a striated intima bounding the 
lumen and groups of regenerating cells \_“Drilsen-Crypten” of 
Erenzel (13), “Driisen” or " Crypten” of Eaussek (12), “ger¬ 
minal buds ” of Miall and Denny (18) and “nidii” of Need¬ 
ham (19)] scattered among their bases; (2) a membrana pro¬ 
pria, or basement membrane; (3) a layer of circular muscles; 
(4) a layer of longitudinal muscles; and (5) a peritoneal mem¬ 
brane. 
A study of the free edge of the epithelial cells shows the 
presence of secretory processes, which are formed by strangula¬ 
tion. The secretory processes are of two kinds; the larger gen¬ 
erally represents a large part of an epithelial cell and some¬ 
times includes its nucleus, while the smaller is much more nu¬ 
merous and never contains a nucleus. These larger secretory 
processes are usually pyriform in shape and protrude far above 
the striated intima of the epithelial cells. In Eigure 11, the 
large secretory process (lsp) has the appearance of having been 
crowded out by the compression of the adjacent cells. The 
smaller kind of secretory processes are stalked granular glob¬ 
ules in direct continuation with the protoplasm of the cell from 
which they have originated (Eig. 11, ssp ). We could observe 
only one way in which the secretory processes became liberated 
into the lumen of the intestine; they were simply constricted 
off from the cell, and were then free to circulate within the in¬ 
testine (Eig. 11, sp). 
The epithelial layer consists of two markedly different parts; 
the elongated, cylindrical epithelial cells, and little groups of 
regenerating cells lying at their bases. On account of the reg¬ 
ular transverse folds of the mid-intestine, the epithelial cells 
