178 Wisconsin Academy of Sciences, Arts, and Letters. 
“Pure alcohol is substituted instead of Compound Tincture of 
Lavender, which, from the variety of its ingredients may produce 
chemical changes. ” This is also true of the New York edition of 
1830. Presumably, the alcohol addition was regarded as a pre¬ 
servative. The Philadelphia edition of 1830, however, came back to 
the original Compound Spirit of Lavender. This remained, until 
in 1880 when it was replaced by Compound Tincture of Lavender. 
This change is one of title only as the composition of the two was 
practically the same. The editors of the United States Dispensa¬ 
tory 103 state that “The spirit of lavender is added to give it taste, 
and prevent its being mistaken for water. ’ ’ 
With the alkali of the arsenical solution the pigment of the red 
saunders possibly combines. (See No. 3Preservation.) 
The French Codex of 1818 uses spirit of melissa as flavoring 
agent, and adds no coloring matter, a precedent apparently fol¬ 
lowed by the German Pharmacopoeia up to this day. 
12.) The volume of the finished product. According to Fowler’s 
formula, the finished product was diluted to exactly one pint or, by 
weight, “fifteen ounces and a half.” The U. S. P. in all its edi¬ 
tions from 1820 to 1870 inclusive directs dilution to one pint. In 
the subsequent editions the ratio of arsenic trioxide to finished 
product is that of one part by weight to 100 parts by volume, what¬ 
ever the amounts of the formula. The corresponding ratio of the 
earlier editions is 0.84 to 100. 
The amounts and ratios of the London and British pharma¬ 
copoeias respectively are herewith tabulated:— 
Pharmacopoeia. 
As 2 0 3 
k 2 co 3 
Vol. of 
product 
Ratio 
London. 
1809 
64 gr. 
64 gr. 
1 pt. 
) 
£ 
0.84 
to 
100 
4 4 
. 1815 
64 gr. 
64 gr. 
1 pt. 
f 
“ 
1851 
80 gr. 
80 gr. 
1 pt. 
[ 
0.84 
to 
100 
British. 
. 1864 
80 gr. 
80 gr. 
1 pt. 
) 
“ 
1885 
87 gr. 
87 gr. 
1 pt. 
't 
0.99 
to 
100 
“ 
. ( 1898 
\m gr. 
00 
03 
hJ 
\ 1 pt. 
i 
“ . 
. } 1898 
( 10 gm. 
( 10 gm. 
( 1000 Cc. 
i 
1.00 
to 
100 
“ 
. 1914 
10 gm. 
10 gm. 
1000 Cc. 
i 
j 
103 13th edition, 1872, p. 1267. 
