186 Wisconsin Academy of Sciences, Arts, and Letters. 
the maximum single dose given, but the maximum amount to be 
given “per diem” is prescribed. “Overprescribing the maximum 
amount in most of the European countries is indicated by having 
the physician place an exclamation mark (!) after such a pre¬ 
scribed dose. This reveals to the pharmacist that the prescriber 
wants the effect of something more than the ‘ average ’ maximum 
dose; this cautions him in his dispensing, and relieves him of the 
responsibility of ‘too large a dose’. 112 ” 
The following table gives the dose of the European pharmaco¬ 
poeias consulted: 
Bose 
1910 German. max, single, 0.5 g. max. daily, 1.5 g. 
1909 Italian................. max. single, 0.5 max. daily, 1.5 
1905 Holland................ max. single, 500 mg. max. daily, 1.5 gm. 
1907 Switzerland............ max. single, 0.5 max. daily, 1.5 
1913 Norwegian....--.... max. single, 0.5 gm. max. daily, 2.0gm. 
1905 Spanish... max. single, 0.6 
1914 British .. max. single, 0.5 centimils. 
1910 U. S.... average 0.2 mils 
1906 Belgian................ no dose given, 
1908 French ................ no dose given, 
1908 Swedish.... no dose given, 
112 Kremers, Ibidem, Cir. 500, p. 2048. 
