188 Wisconsin Academy of Sciences, Arts, and Letters. 
by abundant experience hath been found very helpful and beneficial 
as well in uses medicinal as others,’ No particulars of the in¬ 
gredients or method of manufacture are given.” (Wootton, 
Chronicles of Pharmacy, Yol. II, pp. 161-2.) 
Medical Compound. 
Wilson’s Specification. 
To all to Whom these presents shall come, I, Thomas Wilson, of 
Snow Hill, in the Parish of Saint Sepulchre’s, in the City of 
London, Chymist, send greeting. 
Whereas His most Excellent Majesty King George the Third, 
by his Letters Patent under the Great Seal of Great Britain, bear¬ 
ing date at Westminister, the Sixteenth day of February, in the 
twenty-first year of his reign, did give and grant unto me, the said 
Thomas Wilson, His especial licence that I, the said Thomas Wilson, 
during the term of years therein expressed, should and lawfully 
might use, exercise, and vend, within England, Wales, and Town of 
Berwick-upon-Tweed, my invention of “A Medicinal Composition, 
which after much Experience hath beert found to be an Infallible 
Remedy for Agues and Intermitting Fevers, even in the most ob¬ 
stinate Cases where the Bark and every other Medicine hath proven 
ineffectual;” in which said Letters Patent there is contained a 
provisoe obliging me, the said Thomas Wilson, under my hand and 
seal, to cause a particular description of the nature of the said In¬ 
vention to be inrolled in His Majesty’s High Court of Chancery 
within four calendar months after date of the said recited Letters 
Patent, as in and by the same (relation being thereunto had) may 
more fully and at large appear. 
Now Knowe Ye, that in compliance with the said provisoe, I, 
the said Thomas Wilson, do hereby declare that my said Invention 
of a Medical Composition, which, after much Experience hath been 
found to be an Infallible Remedy for Agues and Intermitting 
Fevers, is described in the Manner following, (that is to say) :— 
Take of centarium minus, or common centaury, any quantity, 
burn it to ashes; take of these ashes, boil them in water for three 
hours, evaporate the liquid to dryness; take this mass, calcine it 
for four or five hours, keeping it constantly stirring. Take cob- 
