CAUSING ACUTE INFECTIONS. 
77 
may be given intravenously or into the muscles. The 
prospect of success in cases where tetanus has already 
developed is not as good as it is in prophylaxis. Park, 
however, mentions 24 consecutive cases of tetanus with 
18 recoveries. 
The Glanders Bacillus (Bacillus Mallei). 
Glanders is a malady which occurs principally 
among horses, but dogs, cats, sheep, and swine are 
also susceptible. In rare instances man acquires the 
disease. It is caused by the Bacillus mallei , a small, 
rod-shaped organism with rounded ends. It can be 
cultivated easily on the ordinary kinds of culture 
media, and stains readily, but unevenly, giving the 
bacillus a granular appearance much likeThe bacillus of 
diphtheria. Heat at 6o° C. will destroy the bacilli in 
two hours and 1 per cent, carbolic acid in thirty 
minutes. Drying destroys them in a short time. In 
water they may live for two months or more. 
The infection in horses occurs generally in the 
nose or mouth, from the entrance of the bacilli through 
cracks or wounds in the mucous membrane. After an 
incubation period of two or three days there is a nasal 
discharge with swelling of the nasal mucous mem¬ 
brane, which later ulcerates. The cervical lymphatic 
glands also swell and may suppurate. The dis¬ 
ease frequently terminates in pneumonia. Infection 
through the skin gives rise to a nodular eruption, the 
nodules later undergoing suppuration. This is called 
farcy. 
