TREATMENT OF GOITRE. 
153 
potassium in doses of 30 grains of each. A marked diminution of the 
swelling and removal of the dyspnoea is said to occur in three weeks. In 
true goitre more active results are obtained by intraparenchymatous 
injections made with a Pravaz syringe, the needle being inserted into 
the tissues of the gland, and from 5 to 15 drops of tincture of iodine 
passed in. Inflammation usually develops, but disappears in eight to 
fourteen days, when the injection may again be used and repeated at 
intervals. Good results have been reported from injection of a 15 pei cent, 
solution of iodoform in aether or glycerine. Moller obtained favourable 
results in a dog from intraparenchymatous injection of a watery 
solution of papain (1 to 10). The swelling in forty-eight hours was 
uniformly soft; on incision the digested parenchyma of the gland was 
discharged as a milky fluid, and although it did not completely dis¬ 
appear, the swelling markedly decreased and the dyspnoea became less. 
In dogs the gland sometimes undergoes cystic changes, producing a 
swelling outwardly resembling an abscess. Should it be laid open, 
however, death generally results (Zschokke). 
More recently very good results have been obtained, both in animals 
and men, from the administration of thyroid juice or extract. Even 
after a few doses of 1* to 7 grains, dogs have shown marked improve¬ 
ment and diminution in the swelling. On the other hand,. Stabel found 
that, in man, neither thyroiodin nor thyroden could be relied on to con¬ 
trol the effects subsequent to the removal of the thyroid gland. 
Rvdvgier, in human patients, recently tried ligature of the arteries of supply 
but their simultaneous ligation was only favourable m parenchymatous goi re. 
In struma fibrosa et cystica the operation was useless. Schmidt used the 
“ ecraseur ” for extirpation in the horse. Massot exposed the gland, drew it 
forward with the fingers, and resorted to torsion before ligaturing. Alter 
dissecting back the skin, Moller lays free the gland with the fingers, and 
ligatures the visible vessels, finally applying a still stronger hgatuie an 
removing the gland above it. Care should be taken not to divide the gland 
too closely, as the ligature may slip off. It is better to leave some gland tissue 
so as to give the ligature a better hold. After-treatment must be legu ate 
according to general principles. Lanzilotti removed a goitre swelling as 
large as a child’s head from a horse. It had developed m six months. re 
right section of the gland was as large as a potato, and was retained 
animal returned to work after a month’s rest. Examination of the tumour 
showed it to be a simple adenoma. Munk’s and Breisacher s expenmen s 
seem to indicate milk diet as a valuable means of treatment Where only 
one side of the gland is diseased, removal of this portion can be undeita e 
"t by .~'W Basedow’s d«... 
thalmic goitre), which Jewsejenko and Cadiot state having observed also in 
the doe and horse. A three year old female pug had a sudden epileptic fit, 
showed marked frequency of the pulse and disturbance of digestion, with 
swelling of the thyroid, exophthalmus and ulceration of the cornea. T e 
eyes were treated with sublimate lotion, the introduction of eserm and 
the application of compresses moistened with 2 per cent, boric acid , 8 diops 
