LESION OF DIFFERENT REGIONS OF THE CEREBRAL HEMISPHERES. 523 
suppuration, the lateral movements of the head, and movements of the eyeballs, 
were seen before the animal passed into the state of semi-coma preceding death. 
Experiment 20 (Plate 25, fig. 57). 
In this animal the frontal lobes were exposed on both sides anterior to the pre¬ 
central (antero-parietal) sulcus, and the convexity of both lobes in advance of this 
sulcus generally seared and broken up by the galvanic cautery. 
On regaining consciousness immediately after the dressing of the wound, the animal 
was able to open both eyes and to make sprawling movements with its limbs. 
Half an hour subsequently it was seen, in trying to walk, to sprawl along on its 
ventral surface, as if unable to keep its head up. It was able, however, when it came 
to the bars of the cage to sit up and try and climb. 
An hour after the operation it was seen, in climbing up the bars of the cage, to let 
its head drop between the bars as if powerless, and it did not turn its head or eyes to 
either side when touched or when sounds were made, though it evidently, by its 
general movements, both felt and heard. 
When the animal was sitting up, which it could do quite well, the head was held in 
the natural position, not drooping and not shaking or oscillating. 
Next day the animal seemed in perfect health, running about restlessly hither and 
thither. There seemed no defect in the power of carrying its head, or in turning its 
head and eyes to either side without turning the trunk. The general motor powers 
were unimpaired. Tactile sensibility in the head and neck and elsewhere appeared 
perfectly normal; and sight, hearing, and the other faculties of sense also unimpaired. 
No physiological deficiency could be discovered. 
On the third day the condition was the same. The animal was in the most constant 
state of activity and restlessness, running about incessantly, and fumbling about 
among the straw, &c., at the bottom of the cage. 
Next day it was watched for a long time, but no defect could be ascertained as 
regards its motor or sensory faculties. Occasionally it would sit still looking vacantly, 
but most commonly it was engaged running about restlessly, or fumbling at the 
bottom of the cage. 
No further change was seen during daily observation for ten days after the opera¬ 
tion, the animal continuing in the same alternately dull and restless condition. 
The weather at the time was intensely cold, and without any other discernible 
cause than this the animal died eleven days after the operation. 
Post-mortem examination .-—The edges of the wound in the scalp had not healed, 
but there was no suppuration or effusion. There was no effusion or sign of inflam¬ 
mation within the skull, and the brain was everywhere normal except in the frontal 
region. 
On the left side the cortex was entirely destroyed over the anterior two-thirds of 
3x2 
