526 
PROFESSORS D. FERRTER A STD G. F. YEO ON THE EFFECTS OF 
More anteriorly stimulation seemed frequently associated with movements of the 
eyeballs to the opposite side, but they fluctuated so that occasionally doubt was 
entertained. But there was no action whatever of the head or trunk. 
Unless the movements of the eyeballs were directly caused by irritation, the results 
of electrisation of the prefrontal lobes must be set down as negative to all external 
appearance. 
X 
The whole convex surface of the prefrontal lobes, in advance of centre 12, was then 
cauterised with the galvanic cautery. The mesial aspect of these regions was also 
cauterised; the anterior part of the falx being divided and tied so as to allow of this 
being done as effectually as possible. Anteriorly the destruction was effected as far 
forward as could he done without injury to the olfactory bulbs. The orbital aspect 
of the lobes was slightly raised so as to allow of complete destruction of the lower 
frontal convolution. 
The cauterisation thus implicated the anterior two-thirds of the three frontal 
convolutions, so far as could be determined before death. 
When the dressings had been applied the animal continued for a short time to 
have muscular twitchings, as if from some irritation of the dura mater, but in little over 
an hour was able to sit up and walk a few steps, though rather shaky. It was able 
to open its eyes, and it withdrew its hands and feet when they were touched. 
A touch on the right ear caused movement of the head to the left, and a touch on 
the left caused movement to the right. 
Next day the animal seemed perfectly recovered. It ran about actively ; took 
things offered it with the utmost precision. Particular attention was paid to the 
movements of the head and eyes. These were evidently retained in their integrity, 
for the animal turned its head to either side without moving its trunk, and forwards 
and backwards with perfect freedom. Hearing was acute and tactile sensibility 
unimpaired everywhere. Smell was retained, judging from the apparent pleasure 
excited by oil of bergamot placed under its nostrils. Ammonia excited active signs of 
irritation in the nostrils. 
No physiological defect could be discovered. Nor could any very definite alteration 
in the animal’s mental character be determined. It seemed only less timid of its com¬ 
panion, and persisted in stealing food out of its hands, though punished every time 
with an angry bite or a tug, But from this time onwards till its death by chloroform, 
eleven weeks after the operation, it continued in perfect health and exhibited no 
perceptible deviation from the normal. 
Post-mortem examination .-—The orifices in the skull in the frontal region were 
covered by membrane continuous with the dura. The dura stripped readily without 
trace of adhesion, everywhere except at the seat of lesion in the prefrontal lobes. 
It was found on removal of the brain that the olfactorv bulbs and tracts were 
*/ 
uninjured. These were removed intact, and without any signs of adhesion. 
Examination of the brain after removal of the adherent membrane revealed an 
