112 
THE CODEX AND THE BRITISH PHARMACOPEIA. 
160. Sulfate de Quinine*. C 40 H 24 Az 2 O 4 ,SO 3 HO,7HO = 436. 
Sulfas Quinicus. Sulphate of Quinine. 
Calisava bark .... One thousand grammes . . . 1000 
Hydrochloric acid . . . Sixty grammes. 60 
Eiver water.Twelve litres or grammes . . . 12000 
Quicklime ..... One hundred grammes .... 100 
Distilled water .... 
Sulphuric acid .... 
Purified animal charcoal . 
In considering theoretically the processes given in the two works for the pre¬ 
paration of this important article, one naturally inclines towards that of the 
P. B. The exhaustion of the bark by cold maceration and percolation rather 
than by boiling, as in the Codex, and the smaller quantity of colouring matter 
taken up, are, at any rate to an experimental operator, advantages not to be 
overlooked. Commercially the preparation of this article will naturally remain 
in the hands of large manufacturers. 
The acid sulphate of quinine is prepared by adding diluted sulphuric acid to 
a neutral sulphate of quinine, evaporating, and setting aside in a cool place that 
crystals may form. The necessity or advantage of such a preparation is difficult 
to discover. 
Of each a sufficiency. 
166. Valerianate d’Atropine. C 34 H 23 AzO 6 ,C 10 H 9 O 3 ,HO = 391. 
Valeras Atr opium. Valerianate of Atropine. 
Valerianic acid .... Q. V. 
Atropine.Q. S. 
Ether.Q. S. 
Dissolve the valerianic acid in the ether, add sufficient atropine to saturate 
the solution and allow the ether to evaporate spontaneously ; the valerianate of 
atropine settles as a light white crust formed by a mass of little crystals. It 
melts at 32°, is very soluble in water, less so in spirit and ether. Not in the 
P. B. What can be the object of uniting valerianic acid and atropine? 
167. Valerianate de Quinine. C 40 I1 24 Az 2 O 4 C 10 H 9 O 3 ,2HO = 435. 
Valerate de Quinine. Valeras Quinicus. Valerianate of Quinine. 
Add a slight excess of valerianic acid to a concentrated alcoholic solution of 
quinine, mix the liquor with twice its volume of water and let.it evaporate 
spontaneously in a stove the temperature of which does not exceed 50°. Vale¬ 
rianate of quinine crystallizes in hexagonal prisms, often aggregated in silky 
masses, it dissolves in 110 parts of cold water and 40 of boiling; it is more 
soluble in alcohol. 
CHAPTER XIX. 
SOAPS. 
168. Savon Amygdalin*. 
Medicinal Soap. Almond Soap. 
Prepared with oil of sweet almonds and solution of caustic soda. 
169. Soap made with purified beef marrow, solution of caustic soda, and 
common salt. 
