ALKALOID IN CITRATE OF IRON AND QUININE. 
159 
From two analyses of twenty-five grains each I obtained 3 77, 3-73, mean 
3 75, equal to 15 per cent, of quinine or 23-437 per cent, of its citrate. The 
dried quinine had a dark blackish-brown colour and resinous appearance, and 
nearly all was soluble in ether, forming a deep reddish-brown solution. 
No. 32. Was composed of small, dark, olive-brown scales, somewhat lighter 
in colour than No. 26, and having more of a greenish tinge. Exposed to the 
air at a temperature of 60° it remained unaltered. It dissolved in water with 
the same facility as No. 26, yielding a dark olive-brown solution with a some¬ 
what reddish tinge, and throwing down a slight deposit on standing. The solu¬ 
tion had an acid reaction on test paper and a strongly bitter, non-chalybeate taste. 
From two analyses of twenty-five grains each I obtained 3-83, 3 - 75, mean 
3’79, equal to 15-16 per cent, of quinine or 23-68 per cent, of its citrate. The 
dried quinine had a dark brown colour and resinous appearance ; it nearly all 
dissolved in ether, yielding a darkish and somewhat turbid solution. 
No. 33. Occurred in smallish scales of an olive-brown colour with a greenish 
tinge. Exposed to the air at a temperature of 60° it was unaltered. It did 
not dissolve in water quite so readily as Nos. 26 and 27, and yielded a dark 
olive-brown solution with a somewhat reddish tinge and slightly turbid. It 
had an acid reaction on test paper, and an intensely bitter non-chalybeate taste. 
From two analyses of twenty-five grains each I obtained 3'89, 3’83, mean 
3- 86, equal to 15-44 per cent, of quinine or 24-12 per cent, of its citrate. The 
dried quinine was of a lightish brown colour and resinous aspect. It nearly all 
dissolved in ether, but the solution w-as dark-coloured and turbid. 
No. 34. Consisted of small scales of a light olive-brown colour with a slight 
greenish tinge. Exposed to the air at a temperature of 60° it was unaffected. 
It was not so readily soluble as Nos. 26 and 27, but yielded a clear solution of 
a dark olive-brown colour with a reddish tinge. The solution had an acid re¬ 
action on test paper and an intensely bitter, non-chalybeate taste. 
From two analyses of twenty-five grains each I obtained 3-98, 4-02, mean 
4- 00, equal to 16 per cent, of quinine or 25 per cent, of its citrate. The dried 
quinine was dark-coloured and had a resinous appearance. It nearly all dis¬ 
solved in ether, yielding a dark-coloured, turbid solution. 
No. 35. Was composed of large, bright, golden-yellow scales very similar to 
those of No. 28, but having more lustre. When exposed to the air at a tem¬ 
perature of 60° no change took place. It dissolved very readily in water, 
forming a fine, clear, golden-yellow solution which had an acid reaction on 
test paper and an intensely bitter, non-chalybeate taste. 
From two analyses of twenty-five grains each I obtained 4-27, 4-23, mean 
4-25, equal to 17 per cent, of quinine or 26-56 per cent, of the citrate. The 
dried quinine was of a light colour and resinous aspect, and dissolved entirely 
in ether, forming a dark clear solution. This specimen was taken from some 
prepared by my own formula, an excess of quinine being purposely introduced. 
It is, perhaps, worthy of note that these specimens appear to have been pre¬ 
pared by two different processes, for Nos. 26, 31, 32, 33, and 34 occurred in 
more or less darkish-coloured scales, yielded dark-coloured solutions, and the 
quinine precipitated from them, when dried, was of a dark colour, whereas Nos. 
25, 27, 28, 29, and 30 had scales of a more or less golden-green colour, yielded 
golden-yellow solutions, and the quinine precipitated from them, when dried, 
was of a light colour. I observed also that the quinine of the last series was 
much whiter at the time of precipitation than that of the first, and separated 
from the solutions with greater facility. No. 35, used in comparison, agreed 
in character with those of the last series. 
Mr. Baker (Swaffham) hoped that at least the names of the makers of a good prepa¬ 
ration would be published, that it might be known where to procure it. 
