NOTES AND ABSTRACTS IN CHEMISTRY AND PHARMACY. 
429 
and magnesium, at a meeting of the Medical Society, and recommended their 
use for the antiseptic treatment of cholera and zymotic diseases generally. In 
the ‘ Lancet ’ of December 7, an account is given of the use of sulplio-carbolate 
of zinc in King’s College Hospital, by Mr. John Wood. It is prescribed in 
aqueous solution of from 3 to 6 grs. to the ounce, as an injection in the treat¬ 
ment of gonorrhoea, and also as a dressing for wounds and sores. Mr. Wood 
has found it of great service in all cases to which the use of carbolic acid is 
applicable. 
The sulpho-carbolates are readily prepared by heating pure carbolic acid with 
oil of vitriol, diluting the mixture with water and saturating the solution with 
a base. By evaporation the sulplio-carbolate of the base may be obtained in 
crystals. 
Sulpho-carbolate of Sodium. — Two volumes of pure carbolic acid are 
mixed with one volume of oil of vitriol in a glass flask, and the mixture heated 
to 280° or 290° F. This temperature is maintained for about five or ten 
minutes, and the liquid is then allowed to cool. About six or eight volumes of 
water are added, and the solution carefully neutralized with carbonate of soda. 
The liquor is evaporated and allowed to crystallize. The salt is deposited in 
rhombic prisms, which should be well drained on white filtering-paper, and 
dried by exposure to the air. The mother-liquor possesses a pinkish-brown 
colour, but with care this may be completely drained away, leaving the crystals 
colourless and pure. 
Sulpho-carbolate of Zinc.— Two volumes of pure carbolic acid are mixed 
with one of oil of vitriol, and heated for five minutes to 290° F., then cooled, 
diluted with water, and gently warmed with a slight excess of pure oxide of 
zinc. The solution is filtered, evaporated, and allowed to crystallize. The salt 
separates iu brilliant right rhombic plates, which are quite colourless after they 
have been well drained on bibulous paper. They should be dried by expo¬ 
sure to the air. Sulpho-carbolate^ of zinc is freely soluble in water and iu al¬ 
cohol. 
The other sulpho-carbolates are obtained in a precisely similar manner to the 
foregoing. The magnesium salt forms white needle-shaped crystals, the ammo¬ 
nium salt is deposited in scales, the barium salt in spherical groups of micro¬ 
scopic needles, and the silver salt crystallizes indistinctly. They are all soluble 
in water and in alcohol. 
These salts in solution give no precipitate with chloride of barium, but if a 
crystal be boiled for several minutes with concentrated nitric acid, and the liquid 
diluted with twice its volume of water, an abundant deposit of picric acid is 
formed, and the filtrate then gives the characteristic reaction of sulphuric acid 
with a salt of barium. 
Sulpho-carbolic acid has been obtained by exactly decomposing sulpho-carbo¬ 
late of baryta with sulphuric acid, and evaporating the filtrate in vacuo. It 
forms slender needle-shaped crystals. 
Sulpho-carbolic acid is analogous to sulpho-vinic acid, having the composition 
(c 0 h 5 ) hso 4 . 
The formula for sulpho-carbolate of sodium is 
(C 0 H 5 )NaSO 4 +Aq, 
and that of sulpho-carbolate of zinc— 
(C 6 H 6 ) 2 Zn"(S0 4 ) 2 +Aq. 
Synonyms. —Sulpho-carbolic acid is otherwise named sulpho-phenic acid o 
plienyl-sulphuric acid. 
