600 
PHARMACEUTICAL MEETING. 
out. It was also obviously a sine qua non that the lighter liquid should not 
be liable to be abstracted by the syrup, or the chloroform would inevitably 
be precipitated in the globular form, as in the case of chloric ether. 
I have succeeded in making such a mixture by reducing the specific gravity 
of the chloroform by means of ether, and shaking them with a definite amount 
of syrup. The chloroform manifests no tendency to separation, even when 
present in the proportion of one-eighth, but a better form is that containing 
one-twelfth. 
The modus operandi is as follows:—Put into a twelve-ounce bottle one 
ounce of chloroform and about three drachms of ether; to the mixture add 
the same volume of the syrup to be employed ; observe carefully the disposi¬ 
tion of the fluids, the chloroform and ether will probably sink, then add gut- 
tatim more ether until the two liquids on being shaken together appear in¬ 
different as to their position in the system; finally fill up the bottle with the 
syrup, and shake well for a minute or two. 
The syrup should not be too dense, or it will be difficult to impart to it suf¬ 
ficient agitation to ensure the complete commixture of the fluids. The syrup 
should be composed of gum and sugar, of honey or treacle ; syrup of sugar 
does not answer well, apparently on account of lacking viscosity. 
The syrup thus formed has the same physical properties as chlorodyne, and, 
like it, is readily miscible with water in any reasonable proportion (one to 
seven), and soluble in the water where the proportion of chloroform is within 
the limits of its solubilit}". 
The advantages attending its use are these:—1st. It does not need special 
precaution when being added to watery fluids, it being at once diffused com¬ 
pletely, and in no case does it give rise to a deposition of large globules of 
chloroform. 2nd. When added in excess of saturation, the undissolved chlo¬ 
roform is deposited in very minute globules, which, after lying together for 
days, show no disposition to combine, but may by a few shakes be dispersed 
evenly through the liquid, forming an emulsion sufficiently permanent to 
enable a dose to be measured without difficulty. 
I will conclude by proposing the following form for an anodyne containing 
chloroform (founded on one published by Dr. Ogden), which will be found to 
remain combined and to mix readily with either spirit or water:— 
Take of Chloroform 5iv; 
Ether 5iss; 
Oil of Peppermint gtt. viij; 
Pesin of Cannabis gr. xvj ; 
Capsicum gr. ij ; 
Macerate for two or three days and filter. (No. 1). 
Then take of Muriate of Morphia gr. xvj ; 
Hydrocyanic Acid Sch. m xcvj ; 
Perchloric Acid; 
Water aa 5s s ; 
Syrup of treacle (or honey), to make in all 4 oz. 
Dissolve the muriate of morphia in about an ounce of syrup, to which has 
been added the perchloric acid and water, assisting solution by a w r ater- 
bath, and wffien cold add the prussic acid. 
Here, as it is absolutely necessary to preserve the relative proportions of 
these potent medicines, and also to include them in a given bulk, the manipu¬ 
lation is not so easy. It is only to be done, so it appears to me, by balancing 
separately the chloroformic tincture with the morphia syrup, and then again 
with a plain syrup to be used in making up the exact measure of the completed 
article. The balancing must be effected by adding water guttatim to a syrup 
