SO-CALLED CARBOLATE OF IODINE. 
717 
His first reply was, “ If any error or inaccuracy can be pointed out in my 
analysis, the pages of the ‘Pharmaceutical Journal 1 will, no doubt, be open to 
any correction or refutation of the statements made.” 
In my second letter, I stated I had received no replies to my questions (two 
of them),— 
1st. Was I or not the individual alluded to? 
2nd. Where did he obtain the article he analysed? 
W. G. Smith’s reply was, “Your demands were unreasonable and unjustifi¬ 
able.” 
W. G. Smith, M.B., charges the unnamed individual with deception and 
fraudulent imposture, and shelters himself from an action for libel and slander, 
as he supposes, by not mentioning my name. 
I then requested Mr. Tichborne, of the Apothecaries’ Hall, to analyse my 
preparation. I give his report, which shows that my preparation, “the carbo¬ 
late of iodine,” is what its name purports it to be, viz. an improvement on the 
original American formula, only much stronger, (the original was so weak that 
it was useless). Miue is, 1^ part of the carbolate containing about 1 part of 
the tinct. iodi B. P., the iodine being combined with the carbolic acid, and 
not present as iodide of ammonium, as stated by W. G^ Smith ; nor did I 
ever state that iodine was free, as my label at foot will show. 
“ Analysis of Carbolate of Iodine by Mr. Tichborne. 
“ As you requested, I have ‘ submitted 1 your carbolate of iodine to a careful 
examination, and beg to place before you the following as the results :— 
“ It contained in the fluid ounce,— 
Alcohol (calculated as rectified spirit, sp. gr. *838) . . 175 grains. 
Glycerine, about.22 ,, 
Iodide of Potassium.. 2*8 ,, 
Iodine (excess over that required by the potassium) . . 5 9 ,, 
Carbolic Acid, not determined. 
“ The remainder consisted of rose-water. It also contained a minute trace 
of lime and phosphoric acid. 
“ The iodine was estimated by evaporating 10 c. c. of the tincture with pure 
soda, and fusing it when dry in a platinum crucible. The mass was then dis¬ 
solved, neutralized with dilute nitric acid, and precipitated and weighed as 
iodide of silver. The potash was weighed as the platinum salt, and the alcohol 
was determined in the distillate obtained from 50 c. c. by taking the gravity. 
“ As regards the question put by you, namely, ‘ If it is made with iodide of 
ammonium? 1 I can positively state that the samples examined are not. When 
boiled with soda or lime, no indication of ammonia whatever was obtained. 
“ To accurately determine this point, 30 c. c. were distilled in a retort with 
an excess of soda; in this case about two-thirds of this liquid was drawn over. 
This distillate was carefully examined for ammonia. A slight indication v'as 
got with Nessler’s test, but not greater than what would be obtained from ordi¬ 
nary distilled water. An attempt was then made to estimate the ammonia in- 
a distillate obtained from a like quantity and in a similar mauner, using a volu¬ 
metric solution of oxalic acid, B. P. ’25 of a degree rendered the solution dis¬ 
tinctly acid. (’25 of a degree would represent *00402 of a grain of ammonia as 
being present in the fluid ounce.) It is therefore self-evident that iodide of 
ammouium does not enter into its composition. 
“ The amount of free hydriodic acid present is trivial (T2 of a grain to the 
ounce, it being determined by a decinormal solution of soda). It is therefore 
evident, from the analysis, that the iodine is mainly combined with the carbol c 
