MATEKIA MEDICA, AND THEEAPEETICS. 
357 
“ 8. Preparations Nos. I. and II. were used as a tonic, with the best results, in doses 
varying from 2 to 4 ounces, thrice daily, by nineteen patients, some of whom had pre¬ 
viously suffered from fever and remained in a debilitated condition. 
TABLE OP PEVER CASES TREATED BY PREPARATIORS OP CINCHONA LEAVES. 
o 
CO 
Typo of 
Fever. 
No. of days 
taking the re¬ 
medy. 
1 
on 1 
<D 
1 
No. of days 
fever was 
cS 
o 
Cm 
O 
6 
No. of d 
taken. 
Present. 
Absent. 
Eemarks. 
1 
Tertian ,,, 
6 
18 
1 
5 
Cured, but had taken large doses of qui- 
2 
Eemitteut 
8 
24 
8 
0 
nine for five days previous to commen¬ 
cing the remedy. 
Fever uninfluenced by the remedy. 
3 
9 
27 
0 
9 
This was a relapse. Took quinine for 
4 
Quotidian 
5 
15 
1 
4 
three days before commencing the re¬ 
medy. 
A mild case. Cured. 
5 
5 
15 
1 
4 
Do. Do. 
6 
6 
18 
3 
3 
Cured. 
7 
2 
6 
0 
2 
Do. A mild case. 
8 
55 
4 
12 
4 
0 
Remedy without effect. 
9 
Tertian ... 
6 
18 
3 
3 
Do., cured by quinine. 
10 
Quotidian 
1 
2 
1 
0 
Remedy nauseated patient. Do. 
11 
6 
18 
2 
4 
Cured. 
12 
55 
5 
15 
2 
3 
Quinine resorted to. 
13 
Febricula. 
5 
15 
1 
4 
A simple case. Cured. 
14 
3 
9 
0 
3 
Do. Do. 
15 
3 
9 
0 
3 
Do. Do. 
16 
Quotidian 
6 
18 
2 
4 
Cured. 
17 
5 
15 
0 
5 
Do. A mild case. 
18 
5 
15 
5 
0 
No effect. An obstinate case in a Bombay 
19 
3 
8 
3 
0 
Marine. Transferred to Bombay. 
Cured by arsenic. 
20 
13 
33 
2 
11 
On each day, when fever occurred, took 
21 
Common 
continued 
7 
21 
0 
7 
15 grains of quinine. 
Cured. 
22 
Remittent 
10 
20 
8 
2 
A veiy obstinate case, still under treat- 
23 
Febricula. 
1 
2 
0 
1 
ment. 
A very mild case. Cured. 
24 
Quotidian 
3 
6 
1 
2 
Do. Do. 
25 
5 
8 
4 
1 
Quinine resorted to. 
26 
55 
4 
8 
2 
2 
A mild case. Cured. 
“ 9. I think that cases Nos. 4, 5, 7, 13, 14, 15, 17, 21, and 23, may fairly be removed 
from the table, as they were cases either of simple febricula, or of such mild inter- 
mittents as might readily have been cured without resorting to any preparation of cin¬ 
chona. 
“10. So far as imj experience enables me to judge, I am led to the conclusion, that in 
simple cases of mild intermittents the remedy may be trusted to, hut that in severe cases of 
malarious fever it is not one on which any great reliance can he placed, and that it is in 
no way comparable to the extracted alkaloid salt, disulphate of quinine, as a genuine 
trustworthy antiperiodic. 
“11. I observe that in Mr. Howard’s report on the cinchona leaves from Ootacamund 
(‘Madras Quarterly Medical Journal/ vol. vii. p. 425), it is stated that the quantity of 
quinine contained in the leaves is very small, viz. 0-11 per cent, of alkaloid, soluble 
