2 
produce the complaint as well as the time of year when the 
creatures enter into the body of the sheep ; the period they 
remain therein ; the ova or eggs they produce ; their exit; 
and the transformations they undergo out of the body from 
the ova to the larvae thence to the pupae ; their supposed 
migration and parasitic condition to molluscs, and their final 
return to their natural habitat, the biliary ducts of the liver, 
for mature development and propagation of their species. 
It is not my intention to go deeply into what is at present 
thought to be the natural history of the Fluke, but merely 
to give an outline—sufficient for the purpose of my paper, 
nor will I enter into the minute details of the numerous 
experiments that have been carried on from time to- time, 
such as endeavouring to produce the disease in healthy 
subjects by giving them the ova or eggs from the bile-ducts 
of rotted animals. My principal object will be that of 
prevention, as little can be done in the way of cure when 
once the animals are stricken, and for the better illustration, 
I will divide my subject into sections. Any one wishing 
for further details on the matter will be amply repaid 
by reading Professor Simonds’, M.R.C.V.S., elaborate and 
exhaustive pamphlet on rot in sheep, which can be had from 
Mr. John Murray, Albemarle Street, London, for seven 
penny stamps, and to which pamphlet I am very much 
indebted for numerous details and valuable information; also 
in part first of the Journal of the Royal Agricultural Society 
of England, for the present year will be found the report of 
interesting experiments now being carried on by Mr. A. P. 
Thomas, Demonstrator of Anatomy, University Museum, 
Oxford, on the development of the Liver Fluke, and in the 
same journal is another article on Rot in Sheep, by Mr. 
Finlay Dun, showing the alarming extent the disease reached 
