118 
MESSRS. J. N. LANGLEY AND H. M. FLETCHER 
Effect of Stimulating the Sympathetic Nerve. 
As far as we know, no attention has been called to the fact that the percentage of 
salts in sympathetic saliva is greater than that which corresponds to its rate of 
secretion, if chorda saliva be taken as a basis of comparison. 
The following experiments bring out clearly the lack of correspondence between 
the rate of flow and the percentage of salts, when sympathetic and chorda saliva are 
compared :— 
'Experiment 3. 
August 5, 1887.—Dog. Weiglit, 5^ kilos. Cannula in right sub-maxillary duct. Cannula for injection 
in left jugular vein. 
2.15. Stimulate cborda, c = 19, no secretion ; c = 18, fairly copious viscid secretion. 
2.25. Stimulate sympathetic, c = 8, very slow secretion. 
2.47-|. Inject 3 mgrm. pilocarpin. Let 25 drops run away, then 
Collect I. The drops in successive 30 sec. were 
4.4.4.4.5.4.4.4.4.3.4.3.3. = 2'6 c.c. in min. 
3.1|. Stimulate sympathetic, c = 8 for 3 min. The secretion stops for 5 min. and then begins 
again, going on at a rate of 1 to 2 drops in 30 sec. 
3.11. Inject 3 mgrm. pilocarpin. 
3.12. Collect II. Drops in each 30 sec. were 
i.-i.i.i.l.l.2.1.2.2.2.2.0.0.0.1.i.i.3.3.4.1.^.]i.2.2.2.2.3.0.1.3.3. 
c = 8 c = 10 c = 15 
1 .2.2 = 2’8 c.c. in 18 min., the actual time of secretion being 16 min. 
During the secretion of the drops doubly underlined, the sympathetic was stimulated. During 
the secretion of the drops singly underlined, the chorda was stimulated for a part of the 
30 sec.; this was done chiefly to prevent the complete cessation of the secretion, which the 
previous trial had shown to be the result of strong stimulation of the symjiathetic. 
3.30. III. Immediately after collecting II., the collection of saliva in III. was begun; thus the 
first part of this was saliva secreted previously and of the same nature as that in II. 
Drops in each 30 sec. were 
2 .1.1.1.2.3.2.2.3.2.3.2.2.3.2.2.2.2.3.2.3.2.2.3.2 = 2-6 c.c. in 12^ min. 
3.42^. IV. Saliva collected immediately after the end of the previous collection, so that this saliva 
contained part of saliva secreted under conditions of III., i.e., from j^ilocarpin alone. The 
sympathetic, during the secretion of the underlined drops in the following, was stimulated 
with weak induction shocks, c = 25 to 30 for 15 to 25 sec. The chorda (at beginning of 
experiment) first gave a secretion with c = 18. 
2.3.0.1.0.0.0.1.L.L.1.2.2.2.3.1.i.i.l.2.3.i.i.2.l.i.l.2.2.2.2.2. 
c = 20 = 25 c = 25 c = 30 
2.1.1.2.1.1.2.1.1.1.1.1.1.1.1.2=3 c.c. in 24 min.j actual time of secretion 
c = 27 
22 min. 
4.9. After about 6 drops had been allowed to run away, the saliva was again collected, the chorda 
