ON THE SECRETION OP SALIVA. 
119 
being stimulated in alternate periods of 30 sec. for 25 to 30 sec., c = 16. Tlie first 
stimulation was for 15 sec. only. The number of drops secreted in each 30 sec. were 
2 . f . 31 
.1.3.1. 
4 . 1 . 4.1 
.4.1.4. 
1.3.1.4 
.1.4.1. 
4.1.3 = 2-8 c.c. in 11| min. 
Time of 
collecting 
saliva. 
Duration 
of secretion 
in min. 
Number 
of c.c. of 
.saliva. 
Eate of 
flow per 
min. in c.c. 
Percentage 
of organic 
substance. 
Percentage 
of .salts. 
Remarks. 
1. 
2.51 - 2.571 
2-6 
•400 
•324 
•728 
Saliva obtained by injecting 
3 mgrm. of pilocarpin. 
3.11. Inject 3 mgrm. pilo¬ 
carpin. ! 
II. 
3.12 -3.30 
16 
2-8 
•175 
1-138 
•726 
Stimulate sympathetic and j 
chorda occasionally. 
III. 
3.30 -3.424 
\01 
2-6 
•208 
•563 
•704 
IV. 
3.42^4.61 
22 
3-0 
•136 
•463 
•711 
Weak stimulation of sympa¬ 
thetic. c = 20 to 30. 
V. 
4.9 -4.201 
2-8 
•243* 
•857 
•623* 
Stimulate chorda, c = 16. 
i 
Here pilocarpin produces a fairly rapid secretion, the saliva having a high 
percentage of salts, viz., ‘728. Whilst the secretion from pilocarpin is going on but 
more slowly, the sympathetic is stimulated ; the rate of secretion of saliva is reduced 
from -I- to f, but the percentage of salts remains nearly the same {'726); the subse¬ 
quent saliva from pilocarpin alone, although faster, has a less percentage of salts 
(•704) ; this is increased by weak stimulation of the sympathetic ('711), although the 
rate of secretion is considerably decreased, and this is the more noteworthy, since the 
percentage of organic substance was very little affected l^y the weak stimulation of 
the sympathetic. Finally, stimidation of the chorda decreases the percentage of salts, 
although about doubling the rate of secretion. 
The divergence from Heidenhain’s law will perhaps be more easily seen, if II.- V. 
are arranged in order of rate of secretion. 
* In V. there is a mixture of salivas secreted at different rates, viz., very neaidy 2-2 c.c. at a rate of 
•37 c.c. a minute, and '6 c.c. at a rate of 'll c.c. a minute. 
It is most unlikely, that a difference in rate of '01 c.c. a minute could cause here a greater difference 
in percentage of salts than ’01. If we take this as being the true relation, we have 
Rate of secretion 
per minute in c.c. 
Percentage of salts. 
v«. 
•37 
•679 
Vj. 
•11 
•419 
