124 
MESSRS. J. N. LAlsTGLET AND H. M. FLETCHER 
In this experiment dyspnoea reduces the rate of secretion of water, hut, except 
when it is prolonged (Y.), does not do so to any great degree. 
Its chief effect is on the secretion of salts; in II. and in IV., although the rate of 
secretion of saliva falls, the percentage of salts rises. The rate of secretion of salts 
is diminished in II., but is increased in IV. ; in the latter case the rate of secretion of 
water is very slightly diminished, so that the increase in the rate of secretion of salts 
may have been due to an increase in the strength of the stimulus caused by a shifting 
of the electrodes on the chorda tympani. At any rate, when the rate of secretion of 
water is diminished to a greater extent, as in II. and as in Experiment 6, the rate 
of secretion of salts falls. 
The rate of secretion of organic substance also falls; that this is not solely due to a 
progressive exhaustion of the gland is indicated by the rate of secretion of organic 
substance being greater in III. than in II. The percentage of organic substance falls 
in each successive sample of saliva secreted; with a constant stimulus this is observed 
normally. But here the drop in the percentage of organic substance does not 
take place regularly; the more dyspnoea decreases the rate of secretion of water, 
the less is the drop in the percentage of organic substance, that is to say, dyspnoea 
decreases the rate of secretion of water more than it decreases the rate of secretion 
of organic substance. 
Experiment 6. 
Jan. 21, 1888.—Dog. Chloroform. (Morphia was not given in this case.) Trachea connected with 
bottle of chloroform and ether. Stimulate chorda, c = 11, secretion very slight; 
repeat, c = 7, fairly rapid secretion, obtain about 1 c.c. Whilst collecting saliva for 
analysis, the secondary coil was in all cases at 7. 
12.0. 1. Stimulate chorda 2 min. 25 sec. Obtain 2 c.c. saliva. 
12.9^. Empty the cannula. Clamp trachea tube, to produce dyspnoea. 
12.10. Stimulate chorda for 2 min. Cannula full (= ^ c.c.), and 8 drops saliva; drops not 
collected. 
12.12. II. Stimulate chorda 1| min.; saliva collected; at end of stimulation unclamp trachea 
tube. 
12.17. Clamp trachea tube. 
12.17^. Stimulate chorda 2 min.; saliva collected ; at end of stimulation unclamp trachea tube. 
12.25. Clamp trachea tube. 
12.254. Stimulate chorda 2J min. ; saliva collected; unclamp trachea tube. Add contents 
cannula to saliva collected. Total amount saliva is 2‘5 c.c. The total time of secretion 
is 6 min. + 1 min. (required to fill the cannula). Stimulate chorda; let 11 droj^s run 
away. 
12.36 ] 
to J 
12.47. 
III. Stimulate chorda 2| min., 
stimulation) and 45 sec. 
= 2 c.c. 
2^ min. (secretion is slow towards end of these periods of 
Total time of secretion is 5f min. Saliva collected 
1 O 
^ Stimulate chorda occasionally; let about 50 drops saliva run away. 
V ago-sympathetic 
1.58 J 
in neck cut. 
