Editors' Note 
This is the first issue of the Recombinant DNA Technicat Builetin pubiished 
fotlowing the approval of the 1978 NIH Guidelines on Recombinant DNA 
Research which became effective January 2. 1979. In light of the significant 
revisions of the 1976 Guidelines, certain changes have also been made in 
the Bulletin. In this and future issues, actions which are being considered by 
NIH and those which have been resolved (such as changes in the Guide¬ 
lines, new HV2 systems, etc.) will be published, as required by the Guide¬ 
lines. in the ACTIONS section. 
The Bulletin was initiated nearly two years ago by Dr. Michael Goldberg with 
the purpose of making available to the scientific community current techni¬ 
cal information about the newly developing recombinant DNA area. Dr. 
Goldberg’s keen interest and unique abilities were essential in the develop¬ 
ment of this rather unusual publication. /\s indicated by the inquiries 
received at the ORDA office, this information reached and was used by a 
large number of people. We greatly appreciate Dr. Goldberg's innovative 
efforts and hard work in developing and publishing the Bulletin. 
Now that we are into a new growth phase--particularly regarding new HV 
systems, new vectors, and the initiation of many experiments which were 
not feasible under the 1976 Guidelines--we hope to continue to be of ser¬ 
vice to the scientific as well as the general community. Any comments or 
suggestions will be appreciated. 
Michael A. Resnick, Ph.D. 
Editor 
Stanley Barban. Ph.D. 
Associate Editor 
