_ 2 - 
Other examples in this report include goldfish from I. M. Obdeyn (RTLA 
1436) and R. R. Cowden (RTLA 1393), a brown trout from Barry J. Stevenson 
(RTLA 1476), two sockeye salmon from Gordon R. Bell (RTLA 1492 and 1493), 
and a black bullhead from C. Dale Becker (RTLA 1496). A rare albino Afri¬ 
can lungfish from N. Herwig with a pigmented malignant melanoma (RTLA 1495) 
and a probable neurofibrosarcoma in a blue gourami from D. 0. Carpenter 
(RTLA 1401) represent two additional neural tumors. 
Another block of cases (RTLA 1531-1597) resulted from an Ohio River 
Valley Water Sanitation Commission survey of the Ohio and Kanawha Rivers 
coordinated by Bill Klein. Surprisingly, only about four neoplastic le¬ 
sions (papillomas) were found in this heavily industrialized watershed. 
Since the method of collection was to rotenone lock chambers, it is quite 
possible that the older bottom feeders most likely to have tumors are 
least likely to migrate through lock chambers, and a different sampling 
method will be needed to collect these fish. 
Interesting reptile lesions received included a l 5 niiphoblastic leu¬ 
kemia in an Indian monitor lizard from J. N. Shively (RTLA 1499), a fibro¬ 
blastic sarcoma in a gopher snake from G. Pendlebury (RTLA 1400), a pan¬ 
creatic adenocarcinoma in a snake ( Spilotes sp.) from Fred Frye (RTLA 
1387), a parathyroid adenoma versus hyperplasia in a Greek tortoise from 
Fred Frye (RTLA 1402), and papillomatosis in an emerald lizard from 0. F. 
Jackson (RTLA 1389). 
An epidermal papilloma versus a low grade papillary carcinoma of a 
tautog was contributed by Richard Wolke (RTLA 1434). Five flatfish epi¬ 
dermal papillomas were received: one from an unpolluted area of Baja 
California contributed by Marjorie Sherwood (RTLA 1390), and four from 
Japan contributed by Keiichi Oishi (RTLA 1486 and 1516) and Takeo Harada 
(RTLA 1487 and 1517). A paper soon to be published in the "Journal of the 
National Cancer Institute" by Wellings et al gives evidence that the X-cells 
in these flatfish tumors and in cod pseudobranch tumors may be unicellular 
organisms. Other possible unicellular organisms in fish are the rodlets 
in the frequently seen rodlet cells several examples of which were contri¬ 
buted by E. K. Miller (RTLA 1463-1467). While some people think the rod- 
lets are most likely some type of protozoans, I can see similarities to 
some of the insect viruses. 
In addition to the hematopoietic neoplasms already mentioned, Elisabeth 
Gateff contributed two mutant Drosophila with "malignant blood neoplasms" 
(RTLA 1489 and 1490). Dr. Gateff has identified more than 15 mutants on 
three chromosomes that result in neoplasms of various origins. Hemato¬ 
poietic fish neoplasms also included a lymphosarcoma in a cutthroat trout 
from Charlie Smith (RTLA 1399) and a northern pike from Gary Hoskins (RTLA 
1442) . 
Liver lesions included a hepatoma in a largescale sucker from C. Dale 
Becker (RTLA 1395), a hepatoma or possibly a hepatoblastoma in a rainbow 
trout from Charlie Smith (RTLA 1469), diethylnitrosamine Induced hepatomas 
in Medaka from Takatoshi Ishikawa (RTLA 1426). Michael Sigel contributed 
a tiger shark with multiple biliary duct cysts (RTLA 1412). 
