-4- 
ceived at least three ichthyematomas or skin tumors in which pegs of epi¬ 
dermis are interacting with dermal connective tissue, similar to the pro¬ 
cess of tooth formation, resulting in variably differentiated levels of 
scale production. 
Among amphibians, 20 Mexican axolotl specimens contributed by Louis 
E. DeLanney (RTLA 1674-1693) had one adenoma, one intradermal melano- 
phoroma, and 18 very interesting cutaneous lesions primarily composed of 
mast cells. The fine structure is currently being studied in an effort 
to differentiate between the possibility these are mast cell tumors 
versus nodules of mastocytosis. A transplanted melanophoroma in a tiger 
salamander from Francis L. Rose (RTLA 1740) appeared to be viable. Two 
hematopoietic neoplasms were accessioned from South African clawed frogs. 
One, contributed by Gerry E. Cosgrove (RTLA 1665), was a lymphosarcoma. 
The cell type of the other case, contributed by R. Verhoeff-de Fremery 
(RTLA 1769), could not be determined. 
Among reptiles were five snake neoplasms: a malignant lymphoma in 
an Indian rock python from Phillip T. Robinson (RTLA 1600), a lympho¬ 
sarcoma in a California king snake from Elliott Jacobson (RTLA 1770), an 
oral squamous versus epidermoid sarcoma in a California king snake from 
James R. Hill (RTLA 1835), a lipoma in a boa constrictor from Fredric L. 
Frye (RTLA 1823), and an angiosarcoma in a timber rattlesnake from Elliott 
Jacobson and S. W. Nielsen (RTLA 1819), but which preliminary electron 
microscopy suggests may actually be a carcinoma. Material from two green 
sea turtles with cutaneous fibropapillomas was received from George H. 
Balazs (RTLA 1767, 1774). A wart-like epidermal papilloma containing 
intranuclear inclusions in a green lizard was contributed by E. Elkan 
(RTLA 1821). 
REFERENCE LIBRARY 
Approximately 360 papers were added to the comprehensive library on 
neoplasms in lower animals bringing the total to 3,510. Except for re¬ 
cent acquisitions and articles that need to be translated, all papers have 
been abstracted by selected key words and computerized. 
PAPERS SINCE 1976 
Harshbarger, J.C. The Role of the Registry of Tumors in Lower Animals in 
the Study of Environmental Carcinogenesis in Aquatic Animals. Ann. N.Y. 
Acad. Sci., 2 ^: 280-289. 1977. 
Rose, F.L. and Harshbarger, J.C. Neoplastic and Possibly Related Skin 
Lesions in Neotenic Tiger Salamanders, Ambystoma tigrinum , from a 
Sewage Lagoon. Science, 196 : 315-317. 1977. 
Harshbarger, J.C., Chang, S.C., and Otto, S.V. Chlamydiae (with Phages), 
Mycoplasmas, and Rickettsiae in Chesapeake Bay Bivalves. Science, 196 : 
666 -668. 1977. 
