462 
The Kurloff-Body 
after the removal of these organs under aseptic precautions. The fact 
that yeasts had been found in the spleen in cases of blastomycosis was 
encouraging. I thought that the Kurloff-body might be the result of 
the chemical activities initiated by a spore either living or after its 
digestion by a leucocyte. This point of view gained support from the 
observation that cultures made from blood alone always, remained 
sterile whereas cultures from the spleen occasionally gave a growth of 
a yeast or mould. 
Much of this work was repeated and carried out with much care, 
yet all of the results are conclusive as disproving Patella’s assertion that 
the Kurloff-body is an intracellular stage of a flagellate. 
It is important that all who experiment with guinea-pigs should be 
familiar with these cell inclusions which seem to be normal to the 
guinea-pig; for I find no less an observer than Mary Rowley, working 
with the assistance of the staff of the Rockefeller Institute, interpreting 
them as caused by the injection of blood from a case of fatal anaemia. 
REFERENCES. 
Cesaris-Demel, a. (1905). Sulla particolare struttura di alcuni gross! leucociti 
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Ehrlich, P. und Lazarus, A. (1898). Die Andmie. 1 Abth. Normale und path. 
Histol. des Blutes (Wien), p. 56. 
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Hiss, P. H. and Zinsser, H. (1910). A Text-Book of Bacteriology (New York), 
pp. 617-633. (For references on blastomycosis.) 
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Loewit, M. (1908). Ueber intranukleare Korper der Lymphocyten und iiber 
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Pappenheih, a. (1907). Riforma Med. No. 23. 
- (1908). Ueber eigenartige Zelleinschlusse bei Leukamie. Berl. klin. Wochen- 
sehr. p. 60. 
Patella, V. (1907). Riforma Med. Nos. 8, 9 and 20. 
- (1908). Kurloff’sche Korper in mononuclearen des Meerschweinschen-blutes 
und ihre protozoische Natur. Berl. klin. Wochemchr. p. 1846. 
Eowley, Mary W. (1908). A fatal anaemia with enormous numbers of circulating 
phagocytes. Journ. Exper. Med. Vol. x. p. 78. Plate X, fig. 6. 
Schilling, V. (1911). Ueber die feinere Morphologic der Kurloff-Korper des 
Meerschweinschens und ihre Aehnlichkeit mit Chlamydozoen-Einschlussen. 
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