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There was one case of ulcerative endocarditis, another of acute pericar¬ 
ditis and peritonitis the origin of which could not be traced, and in yet 
another case there was an abscess in the muscle substance near the apex of 
the heart. In the last case there was an old sinus in the axilla. 
I include in this series a large solitary splenic abscess. As is usual 
with such splenic abscesses there was no other associated disease and no 
ulceration of any part of the alimentary tract. No amcebse were found. 
The abscess had been opened during life by operation and had also burst 
into the peritoneum. Various bacteria were found in the contents of the 
abscess but were probably secondary. 
Cultures made from blood or spleen in the cases of Sepsis showed the 
organisms to be Staphylococus pyogenes aureus and not Streptococci. This 
prevalence of general infections by Staphyloccocus renders it unlikely that 
good results could be anticipated from the use of antistreptoccic serum. 
As regards lower animals. The septicaemia of rabbits is a cause of 
heavy mortality amongst them. It appears to originate de novo and affect 
simultaneously four or five. Prompt removal of the other unaffected 
rabbits from the flock and successive removals if any more are attacked 
usually suffices to limit the epidemic. The organisms are found usually in 
pure culture both in the affected lungs and in the cardiac blood, and are those 
commonly described for this affection. 
Though fatal to guinea-pigs when injected intraperitoneally it does 
not seem to be communicable to them under natural conditions. 
Haemorrhagic Septicaemia in cattle has not been observed by me. This 
disease is so frequently confused with Rinderpest that it is possible some of 
the described epidemics of Rinderpest may have been Haemorrhagic 
Septicaemia, but there is no satisfactory evidence that such is the case. The 
outbreaks of Rinderpest in 1903 and 1904 were certainly that disease and not 
Haemorrhagic Septicaemia. 
Rats do not appear to develope any epidemic disease either naturally or 
in confinement here. Many organisms, some of them occurring in natural 
waters, were fatal to rats when injected, but other rats confined in the same 
cages were not infected. The same organisms given by the mouth in food 
produced no effect. These experiments were made with a view to the 
destruction of rats, as this is a matter of first importance in connection with 
Sugar and other plantations. 
Infective Granulomata. 
Of the infective granulomata other than Tubercle and Leprosy, Syphilis 
is the most important. Syphilitic lesions of the internal organs were found 
in 7 cases and were definitely the cause of death in 2. In many other cases 
there were external lesions, of the disease. On the whole, considering the 
frequency of the disease, the small mortality, the absence of cerebro-spinal 
cases, including Tabes dorsalis, is satisfactory. 
The only special lesion that is of importance because so often overlooked 
and so likely to be confused with dysentery is the Proctitis referred to in 
that connection. 
Two of the cases included on account of their symptomology with 
Malignant disease probably belong to the class of granulomata. In neither 
case was there any evidence of syphilis. 
